134435-25-9Relevant academic research and scientific papers
Palladium-Catalyzed Direct Decarbonylative Phosphorylation of Benzoic Acids with P(O)–H Compounds
Zhang, Ji-Shu,Chen, Tieqiao,Han, Li-Biao
supporting information, p. 1148 - 1153 (2020/02/27)
A direct decarbonylative phosphorylation of benzoic acids catalyzed by palladium was disclosed. Under the reaction conditions, a wide range of benzoic acids coupled readily with all the three kinds of P(O)–H compounds, i.e. secondary phosphine oxides, H-phosphinates and H-phosphonates, producing the corresponding organophosphorus compounds in good to high yields. This reaction could be conducted at a gram scale and applied in the late-stage phosphorylative modification of carboxylic acids drug molecules. These results well demonstrated the potential synthetic value of this new reaction in organic synthesis.
Aromatic phosphorus oxide compounds and preparation method for aromatic phosphorus oxide medicines of same
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Paragraph 0061-0062, (2019/12/25)
The invention discloses a plurality of aromatic phosphorus oxide compounds and a preparation method of aromatic phosphorus oxide medicines of the same. The preparation method comprises the following steps: weighing 1.2 times equivalent of aromatic carboxy
Arenediazonium tetrafluoroborates in palladium-catalyzed C-P bond-forming reactions. Synthesis of arylphosphonates, -phosphine oxides, and -phosphines
Berrino, Roberta,Cacchi, Sandro,Fabrizi, Giancarlo,Goggiamani, Antonella,Stabile, Paolo
supporting information; experimental part, p. 4518 - 4520 (2010/11/17)
A novel palladium-catalyzed synthesis of arylphosphonates from arenediazonium tetrafluoroborates and triethylphosphite or diethylphosphite is presented. The reaction tolerates useful substituents including bromo, chloro, nitro, ether, cyano, keto, and ester groups, can be performed as a one-pot process from anilines omitting the isolation of arenediazonium salts, and can be extended to the preparation of arylphosphine oxides and arylphosphines.
Axially Dissymmetric Diphosphines in the Biphenyl Series: Synthesis of (6,6'-Dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine) ('MeO-BIPHEP') and Analogues via an ortho-Lithiation/Iodination Ullmann-Reaction Approach
Schmid, Rudolf,Foricher, Joseph,Cereghetti, Marco,Schoenholzer, Peter
, p. 370 - 389 (2007/10/02)
The new axially dissymmetric diphosphines (R)- and (S)-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine) ((R)- and (S)-5a; 'MeO-BIPHEP') and the analogues (R)- and (S)-5b and 5c have been synthesized in enantiomerically pure form.These lignands hav
