134451-89-1Relevant academic research and scientific papers
Synthesis of N-Acetyl-D- and -L-glucosamine, cis-3,5-Cyclohexadiene-1,2-diol as Building Block for the Preparation of Modified Hexoses
Lehmann, Jochen,Moritz, Andreas
, p. 937 - 940 (2007/10/02)
Six-membered, unsaturated carbocycles are versatile starting materials for the preparation of a large variety of modified hexoses.This is exemplified by the synthesis of N-acetylglucosamine 12 as a racemate from cis-3,5-cyclohexadiene-1,2-diol (1), which can be obtained by microbial oxidation of benzene.In this special case D- and L-N-acetylglucosamine could be differentiated by enzymatic D-galactosylation of the former. Key Words: Microbial oxidation / Epoxides / Ozonolysis / Hemiacetals / Transgalactosylation, enzymatic
