1344711-06-3Relevant articles and documents
Copper-catalyzed trifluoromethylation of unactivated olefins
Parsons, Andrew T.,Buchwald, Stephen L.
, p. 9120 - 9123 (2011)
Activating the inactive: A copper-catalyzed allylic trifluoromethylation of unactivated terminal olefins proceeds under mild conditions to produce linear allylic trifluoromethylated products with high E/Z selectivity (see scheme). The reaction can be applied to a range of substrates bearing numerous functional groups. Furthermore, the reaction is scalable and amenable to a benchtop setup. Copyright