134529-31-0Relevant academic research and scientific papers
Synthesis, cytotoxic activity, and tubulin polymerization inhibitory activity of new pyrrol-2(3H)-ones and pyridazin-3(2H)-ones
Abbas, Samar Hafez,Abuo-Rahma, Gamal El-Din A.A.,Abdel-Aziz, Mohamed,Aly, Omar M.,Beshr, Eman A.,Gamal-Eldeen, Amira M.
, p. 46 - 62 (2016/04/05)
A series of new pyrrol-2(3H)-ones 4a-f and pyridazin-3(2H)-ones 7a-f were synthesized and characterized using different spectroscopic tools. Some of the tested compounds revealed moderate activity against 60 cell lines. The E form of the pyrrolones 4 show
Stereospecific Palladium(II)-Catalyzed Cyclocarbonylation of 3-Aryl-1-propynes and Iodoarenes of Acid Chlorides To Form (E)-3-Arylidenebutenolides
Huang, Yujin,Alper, Howard
, p. 4534 - 4536 (2007/10/02)
Iodoarenes react with 3-aryl-1-propynes and carbon monoxide, in the presence of palladium acetate and triphenylphosphine, to form (E)-arylidenebutenolides in 33-88percent isolated yields.The same product is formed by substitution of acid chloride for a io
