1345509-84-3Relevant academic research and scientific papers
One-pot synthesis of 1,2,4,5-tetrasubstituted imidazoles by a tandem three-component reaction of hydroxylamines, aldehydes and 2-azido acrylates
Hu, Bao,Ai, Ning,Wang, Zhao,Xu, Xiaoliang,Li, Xiaonian
experimental part, p. 222 - 228 (2012/06/01)
The reaction of nitrones, formed in situ by reaction of hydroxylamines and aldehydes, with 2- azido acrylates results in the formation of 1,2,4,5-tetrasubstituted imidazoles has been developed. This three-component reaction allows for the formation of a diverse array of imidazole derivatives with moderate to excellent yields. ARKAT-USA, Inc.
Catalyst-free preparation of 1,2,4,5-tetrasubstituted imidazoles from a novel unexpected domino reaction of 2-azido acrylates and nitrones
Hu, Bao,Wang, Zhao,Ai, Ning,Zheng, Jie,Liu, Xing-Hai,Shan, Shang,Wang, Zhongwen
experimental part, p. 6362 - 6365 (2012/01/14)
A highly efficient and convenient method for the synthesis of 1,2,4,5-tetrasubstituted imidazoles from readily accessible 2-azido acrylates and nitrones has been developed. This reaction proceeded under mild conditions without the assistance of any metal,
