134575-07-8

Basic information

• Product Name: exo-3-Benzyl-3-azabicyclo[3.1.0]hexane-6-methanol
• Synonyms: exo-3-Benzyl-3-azabicyclo[3.1.0]hexane-6-methanol;exo-3-Benzyl-3-azabicyclo...;(1R,5S,6R)-3-Aza-3-benzyl-6-(hydroxymethyl)bicyclo[3.1.0]hexane 95+%;[(1R,5S,6R)-3-Aza-3-benzylbicyclo[3.1.0]hex-6-yl]methanol;[(1S,5R)-3-Benzyl-3-azabicyclo[3.1.0]hexan-6-yl]Methanol;(1R,5S,6R)-3-Aza-3-benzyl-6-(hydroxymethyl)bicyclo[3.1.0]hexane;-3-Benzyl-3-azabicyclo[3.1.0]hexan-6-yl);EOS-61752
• CAS NO: 134575-07-8
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.28018
• Mol File: 134575-07-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 312.3±15.0 °C(Predicted)
• Appearance: /
• Density: 1.158±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.94±0.10(Predicted)
• CAS DataBase Reference: exo-3-Benzyl-3-azabicyclo[3.1.0]hexane-6-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: exo-3-Benzyl-3-azabicyclo[3.1.0]hexane-6-methanol(134575-07-8)
• EPA Substance Registry System: exo-3-Benzyl-3-azabicyclo[3.1.0]hexane-6-methanol(134575-07-8)

Safety Data

• Hazardous Substances Data: 134575-07-8(Hazardous Substances Data)

Usage

General Description

Exo-3-Benzyl-3-azabicyclo[3.1.0]hexane-6-methanol is a chemical compound with a unique molecular structure consisting of a bicyclic ring system containing a nitrogen atom and a benzyl group. It is a derivative of the azabicyclohexane family, and it contains a hydroxyl group at the sixth position. exo-3-Benzyl-3-azabicyclo[3.1.0]hexane-6-methanol has potential applications in organic synthesis and medicinal chemistry due to its structural features and properties. It may be used as a building block in the synthesis of various pharmaceutical compounds and as a starting material for the development of new drug candidates with potential therapeutic benefits. Its specific properties and potential applications warrant further research and exploration in the field of organic chemistry.

Upstream product

• 146726-13-8 3-benzyl-3-azabicyclo[3.1.0]hexane-2,4-dione-6-carboxylic acid ethyl ester 
• 13949-99-0 trans,meso-cyclopropanetricarboxylic acid triethyl ester 
• 705-35-1 trans,meso-1,2,3-cyclopropanetricarboxylic acid 
• 134575-05-6 ethyl 5-benzyl-4,6-dioxo-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrazole-3-carboxylate 
• 1366657-90-0 (1R,5S,6r)-3-benzyl-2,4-dioxo-3-azabicyclo[3.1.0]hexane-6-carboxylic acid 
• 187681-87-4 (1R,5S,6s)-2,4-dioxo-3-oxabicyclo[3.1.0]hexane-6-carboxylic acid 
• 134575-06-7 ethyl (1α,5α,6α)-3-benzyl-3-azabicyclo[3.1.0]hexane-2,4-dione-6-carboxylate 
• 1631-26-1 1-benzyl-1H-pyrrole-2,5-dione 

Downstream Products

• 134575-13-6 (1α,5α,6α)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane 
• 134575-08-9 [1α,5α,6α]-3-Benzyl-3-azabicyclo[3.1.0]hexane-6-carboxaldehyde 
• 134575-17-0 tert-butyl (1R,5S,6R)-3-azabicyclo[3.1.0]hexan-6-ylcarbamate 
• 134575-10-3 [1α,5α,6α]-6-Aminomethyl-3-benzyl-3-azabicyclo[3.1.0]hexane 
• 134575-12-5 (1α,5α,6α)-6-(tert-butoxycarbonyl)aminomethylene-3-azabicyclo[3.1.0]hexane 
• 134575-14-7 benzyl (1α,5α,6α)-6-hydroxymethyl-3-azabicyclo[3.1.0]hexan-3-ylcarboxylate 
• 134575-15-8 (1α,5α,6α)-3-(benzyloxycarbonyl)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid 
• 134575-11-4 ((1R,5S,6S)-3-Benzyl-3-aza-bicyclo[3.1.0]hex-6-ylmethyl)-carbamic acid tert-butyl ester 
• 146726-08-1 (1α,5α,6α)-6-tert-butoxycarbonylamino-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid benzyl ester 
• 925457-08-5 1-(2,4-difluorophenyl)-7-[(1α,5α,6α)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid 
• 925457-09-6 1-(2,4-difluorophenyl)-7-[(1α,5α,6α)-6-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-3-azabicyclo[3.1.0]hex-3-yl]-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid 
• 1366664-25-6 [(1R,5S,6r)-3-benzyl-3-azabicyclo[3.1.0]hex-6-yl]methyl methanesulfonate 
• 1173177-20-2 C₁₈H₂₄ClFN₂O₂ 
• 1173177-23-5 C₂₃H₂₈ClFN₄O₃ 

Relevant articles and documents

Synthesis of new fluoroquinolones and evaluation of their in vitro activity on Toxoplasma gondii and Plasmodium spp.

The synthesis of four new computer-designed fluoroquinolones which have been predicted by QSAR analysis to be active against the protozoa Toxoplasma gondii is described. These compounds are inhibitory in vitro for T. gondii. One of these compounds has a remarkably high activity comparable to that of trovafloxacin. It combines the basic cyclopropyl-quinoline structure of gatifloxacin or moxifloxacin with the C-7 6-amino-3-azabicyclo[3.1.0]hexyl side chain of trovafloxacin. The four compounds are also inhibitory for blood stages of Plasmodium falciparum though at high concentration. These results confirm the potential of quinolones as anti-T. gondii and antimalarial drugs but also show that the QSAR models for T. gondii cannot be reliably extended for screening antimalarial activity.