1345829-69-7Relevant academic research and scientific papers
The design, synthesis and biological evaluation of novel URB602 analogues as potential monoacylglycerol lipase inhibitors
Szabo, Monika,Agostino, Mark,Malone, Daniel T.,Yuriev, Elizabeth,Capuano, Ben
, p. 6782 - 6787 (2011/12/22)
We have synthesised an extensive series of URB602 analogues as inhibitors of monoacylglycerol lipase (MAGL), which is the major enzyme responsible for metabolising the endocannabinoid 2-arachidonylglycerol. The recently identified crystal structure of MAG
