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1345964-75-1

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1345964-75-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1345964-75-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,4,5,9,6 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1345964-75:
(9*1)+(8*3)+(7*4)+(6*5)+(5*9)+(4*6)+(3*4)+(2*7)+(1*5)=191
191 % 10 = 1
So 1345964-75-1 is a valid CAS Registry Number.

1345964-75-1Downstream Products

1345964-75-1Relevant articles and documents

Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor

Patnaik, Samarjit,Marugan, Juan J.,Liu, Ke,Zheng, Wei,Southall, Noel,Dehdashti, Seameen J.,Thorsell, Annika,Heilig, Markus,Bell, Lauren,Zook, Michelle,Eskay, Bob,Brimacombe, Kyle R.,Austin, Christopher P.

, p. 9045 - 9056 (2014/01/06)

The discovery and characterization of a novel chemical series of phosphorothioyl-containing imidazopyridines as potent neuropeptide S receptor antagonists is presented. The synthesis of analogues and their structure-activity relationship with respect to the Gq, Gs, and ERK pathways is detailed. The pharmacokinetics and in vivo efficacy of a potent analogue in a food intake rodent model are also included, underscoring its potential therapeutic value for the treatment of sleep, anxiety, and addiction disorders. This article not subject to U.S. Copyright. Published 2013 by the American Chemical Society.

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