4805-70-3

Basic information

• Product Name: 3-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIDINE
• Synonyms: 3-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIDINE
• CAS NO: 4805-70-3
• Molecular Formula: C₈H₇BrN₂
• Molecular Weight: 211.06
• Mol File: 4805-70-3.mol

Chemical Properties

• Melting Point: 73 °C
• Boiling Point: 1.6 g/cm³
• Appearance: /
• Density: 1.60±0.1 g/cm3(Predicted)
• PKA: 6.05±0.10(Predicted)
• CAS DataBase Reference: 3-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIDINE(4805-70-3)
• EPA Substance Registry System: 3-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIDINE(4805-70-3)

Safety Data

• Hazardous Substances Data: 4805-70-3(Hazardous Substances Data)

Usage

Uses

Used in Research Applications:
3-Bromo-2-methylimidazo[1,2-a]pyridine is used as a research chemical for the synthesis and study of various organic compounds and their properties. Its unique structure allows for exploration in the fields of organic chemistry and heterocyclic chemistry.
Used in Laboratory Settings:
In laboratories, 3-Bromo-2-methylimidazo[1,2-a]pyridine is used as a reagent or intermediate in the preparation of other complex molecules. Its role in these settings is crucial for advancing scientific understanding and developing new chemical entities.

Upstream product

• 128-08-5 N-Bromosuccinimide 
• 504-29-0 2-aminopyridine 
• 598-31-2 1-bromoacetone 
• 13061-96-6 dihydroxy-methyl-borane 
• 1373338-15-8 2-iodoimidazo[1,2-a]pyridine 
• 3999-05-1 2-chloroimidazo[1,2-a]pyridine 
• 92351-15-0 2-amino-1-(prop-2-yn-1-yl)pyridin-1-ium bromide 
• 934-37-2 2-methylimidazo[1,2-a]pyridine 

Downstream Products

• 1246184-22-4 N-(2-chloro-5-(2-methylimidazo[1,2-a]pyridin-3-yl)pyridin-3-yl)-4-fluorobenzenesulfonamide 
• 1345964-72-8 3-(diphenylphosphoryl)-2-methylimidazo[1,2-a]pyridine hydrochloride 
• 1366591-20-9 2-methyl-3-(o-tolyl)imidazo[1,2-a]pyridine 
• 1345964-75-1 3-(hydroxydiphenylmethyl)-1,2-dimethylimidazo[1,2-a]-pyridin-1-ium trifluoroacetate 
• 1345964-73-9 (2-methylimidazo[1,2-a]pyridin-3-yl)diphenylmethanol 
• 1345964-66-0 3-(diphenylphosphorothioyl)-2-methylimidazo[1,2-a]pyridine hydrochloride 
• 1128191-81-0 4-chloro-3-(2-methylimidazo[1,2-a]pyridin-3-yl)aniline 

Relevant articles and documents

Ultrasound-Promoted and Base-Mediated Regioselective Bromination of Imidazo[1,2- a ]pyridines with Pyridinium Tribromide

By using pyridinium tribromide as the bromo source, an efficient- and practical protocol for the synthesis of C3-brominated imidazo-[1,2- a ]pyridines through ultrasound-promoted and Na 2CO 3-mediated regioselective bromination of im

Visible light-mediated photocatalytic bromination of 2-arylimidazo[1,2-a]pyridines using CBr4 as bromine source

The photocatalytic bromination of 2-arylimidazo[1,2-a]pyridines is described in this paper. This reaction uses the readily accessible and shelf-stable CBr4 as a bromine source. This photocatalytic system is shown to serve as a convenient and pr

Chemodivergent synthesis of: N -(pyridin-2-yl)amides and 3-bromoimidazo[1,2- a] pyridines from α-bromoketones and 2-aminopyridines

N-(Pyridin-2-yl)amides and 3-bromoimidazo[1,2-a]pyridines were synthesized respectively from α-bromoketones and 2-aminopyridine under different reaction conditions. N-(Pyridin-2-yl)amides were formed in toluene via C-C bond cleavage promoted by I2/s

K2S2O8-Mediated halogenation of 2-arylimidazo[1,2-a]pyridines using sodium halides as the halogen sources

A convenient halogenation of 2-arylimidazo[1,2-a]pyridines using sodium chloride/bromide/iodide as the halogen sources in the presence of K2S2O8 as an easy-to-handle oxidizing agent was developed. The present work offers a

Transition-metal-free regioselective C-H halogenation of imidazo[1,2-: A] pyridines: Sodium chlorite/bromite as the halogen source

A facile transition-metal-free regioselective halogenation of imidazo[1,2-a]pyridines using sodium chlorite/bromite as the halogen source is presented. The reaction has provided an efficient method for the formation of C-Cl or C-Br bonds to synthesize 3-c

Regiocontrolled functionalization of 2,3-dihalogenoimidazo[1,2-a]pyridines by Suzuki-Miyaura and Sonogashira cross-coupling reactions

An efficient method for regiocontrolled functionalization of 2,3-dihalogenoimidazo[1,2-a]pyridine was developed. This sequence allowed the selective introduction of aryl, heteroaryl, alkyl and alkynyl substituents at both 2- and 3-positions, by using Suzu

Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor

The discovery and characterization of a novel chemical series of phosphorothioyl-containing imidazopyridines as potent neuropeptide S receptor antagonists is presented. The synthesis of analogues and their structure-activity relationship with respect to the Gq, Gs, and ERK pathways is detailed. The pharmacokinetics and in vivo efficacy of a potent analogue in a food intake rodent model are also included, underscoring its potential therapeutic value for the treatment of sleep, anxiety, and addiction disorders. This article not subject to U.S. Copyright. Published 2013 by the American Chemical Society.

INHIBITORS OF PI3 KINASE

The present invention relates to compounds of Formula I, II or III or a pharmaceutically acceptable salt thereof; methods of treating diseases or conditions, such as cancer, using the compounds; and pharmaceutical compositions containing the compounds, wherein the variables are as defined herein

Bicyclic pyridines which are angiotensin II inhibitors

The bicyclic derivatives of pyridines of the formula STR1 and their non-toxic, pharmaceutically acceptable salts and a process and intermediates for their preparation which compounds are inhibitors of angiotensin II effects, particularly a vasoconstrictor