1345969-97-2Relevant academic research and scientific papers
Synthesis of purine modified 2′-C-methyl nucleosides as potential anti-HCV agents
Zhang, Hong-Wang,Zhou, Longhu,Coats, Steven J.,McBrayer, Tamara R.,Tharnish, Phillip M.,Bondada, Lavanya,Detorio, Mervi,Amichai, Sarah A.,Johns, Melissa D.,Whitaker, Tony,Schinazi, Raymond F.
, p. 6788 - 6792 (2011/12/22)
Based on the anti-hepatitis C activity of 2′-C-methyl-adenosine and 2′-C-methyl-guanosine, a series of new modified purine 2′-C-methyl nucleosides was prepared as potential anti-hepatitis C virus agents. Herein, we report the synthesis of both 6-modified
