1345969-99-4 Usage
Molecular Structure
Contains a purine ring and ribofuranosyl moiety
Chemical Modification
Addition of benzoate groups and a methyl group to the ribofuranosyl moiety
Type
Modified nucleoside derivative
Biological Significance
Potential to mimic natural nucleosides
Pharmacological Significance
Potential to interfere with cellular processes like DNA replication and RNA transcription
Value in Drug Discovery
Valuable compound for drug discovery and development in nucleoside chemistry and biochemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1345969-99-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,4,5,9,6 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1345969-99:
(9*1)+(8*3)+(7*4)+(6*5)+(5*9)+(4*6)+(3*9)+(2*9)+(1*9)=214
214 % 10 = 4
So 1345969-99-4 is a valid CAS Registry Number.
1345969-99-4Relevant academic research and scientific papers
Synthesis of purine modified 2′-C-methyl nucleosides as potential anti-HCV agents
Zhang, Hong-Wang,Zhou, Longhu,Coats, Steven J.,McBrayer, Tamara R.,Tharnish, Phillip M.,Bondada, Lavanya,Detorio, Mervi,Amichai, Sarah A.,Johns, Melissa D.,Whitaker, Tony,Schinazi, Raymond F.
body text, p. 6788 - 6792 (2011/12/22)
Based on the anti-hepatitis C activity of 2′-C-methyl-adenosine and 2′-C-methyl-guanosine, a series of new modified purine 2′-C-methyl nucleosides was prepared as potential anti-hepatitis C virus agents. Herein, we report the synthesis of both 6-modified
