134616-46-9

Upstream product

• 6270-74-2 3-oxo-1,4-benzothiazin-2-ylacetic acid 
• 500551-65-5 3-m-tolylcarbamoyl-acrylic acid methyl ester 
• 42537-50-8 (Z)-4-oxo-4-(m-tolylamino)but-2-enoic acid 
• 915711-58-9 3-m-tolylcarbamoyl-acrylic acid methyl ester 
• 137-07-5 2-amino-benzenethiol 
• 134616-44-7 2(H)-oxo-3,3a-dihydrofuro<3,2-b><1,4> benzothiazine 
• 108-44-1 1-amino-3-methylbenzene 

Downstream Products

• 134616-48-1 1-m-Tolyl-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 

Relevant academic research and scientific papers

Synthesis and antifungal activity of N-(alkyl/aryl)-2-(3-oxo-1,4- benzothiazin-2-yl)acetamide

A series of N-(alkyl/aryl)-2-(3-oxo-1,4-benzothiazin-2-yl)acetamide have been synthesized by condensation of substituted amines with maleic anhydride (MA) followed by cyclization with o-aminothiophenol (o-ATP). All the compounds have been screened for their antifungal activity against Tricophyton rubrum, Epidermophyton floccosum and Malassazia furfur. In the primary screening, some of the compounds exhibited appreciable activity. The structures of the synthesized compounds 7a-z have been established on the basis of elemental analysis and spectral data.

Synthesis and biological activity of 2-oxo-1,2,3,3a-tetrahydropyrrolo-benzothiazines

A series of oxo-1,2,3,3a-tetrahydropyrrolbenzothiazines (5) has been prepared and tested for their CNS and anti-inflammatory activities.