6270-74-2

Usage

InChI:InChI=1/C10H9NO3S/c12-9(13)5-8-10(14)11-6-3-1-2-4-7(6)15-8/h1-4,8H,5H2,(H,11,14)(H,12,13)/p-1/t8-/m1/s1

Upstream product

• 106660-02-0 (Z)-(3'-oxo-3',4'-dihydro-2'H-1',4'-benzothiazin-2'-ylidene)acetic acid 
• 110-16-7 maleic acid 
• 137-07-5 2-amino-benzenethiol 
• 64-17-5 ethanol 
• 90704-68-0 2'-mercapto maleianilic acid 
• 2756-87-8 methyl hydrogen fumarate 
• 7291-93-2 (2-nitro-phenylsulfanyl)-succinic acid dimethyl ester 
• 3052-50-4 monomethyl maleate 
• 108-31-6 maleic anhydride 
• 7028-52-6 (4-hydroxy-3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-acetic acid 
• 923-06-8 bromosuccinic acid 
• 110-17-8 (2E)-but-2-enedioic acid 

Downstream Products

• 7556-63-0 3,4-dihydro-2-methoxycarbonylmethyl-3-oxo-2H-1,4-benzothiazine 
• 106691-38-7 N-(4-Methoxy-phenyl)-2-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-acetamide 
• 134616-45-8 2-(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-N-o-tolyl-acetamide 
• 134616-50-5 1-(3-chlorophenyl)-2-oxo-1,2,3,3a-H-tetrahydropyrrolo<3,2-b><1,4> benzothiazine 
• 134616-48-1 1-m-Tolyl-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 134616-49-2 1-p-Tolyl-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 134616-47-0 1-o-Tolyl-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 106691-37-6 2-(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-N-p-tolyl-acetamide 
• 134616-46-9 2-(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-N-m-tolyl-acetamide 
• 101350-88-3 (3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-acetic acid anilide 
• 106691-40-1 N-(3-chlorophenyl)-2-(3-oxo-1,4-benzothiazin-2-yl) acetamide 
• 2694-32-8 1-(4-methoxy-phenyl)-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 2694-31-7 1-phenyl-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 82191-17-1 ethyl 2-(3,4-dihydro-3-oxo-2H-1,4-benzothiazin-2-yl)acetate 

Relevant academic research and scientific papers

Sulfuryl Chloride Promoted gem -Dichlorination-Dehydrochlorination in Alkyl Benzothiazinylacetates: Synthesis of the Skeleton of Trichochrome Pigments

Chemo- and stereoselective total synthesis of the basic trichochrome skeleton is described starting from o-aminothiophenol and maleic anhydride in very good overall yield. The process involves the synthesis of the corresponding 1,4-benzothiazin-2-ylacetates followed by their sulfuryl chloride induced dihalogenation-dehydrohalogenation and a second condensation with o-aminothiophenol as key steps.

Substituted amide phenol compound and its preparation method, pharmaceutical composition and use thereof

The invention discloses substituted-amide phenolic compounds, their preparation method, a pharmaceutical composition and an application thereof. The compounds have a structure as shown in the general formula I, wherein Z, L and Q are as defined in the spe

PEPTIDE DEFORMYLASE INHIBITORS

Benzothiazine compounds of the general formula (I) and pharmaceutically acceptable salts or esters thereof are peptide deformylase inhibitors useful in the treatment or prevention of infections and other diseases in which peptide deformylases are involved

New Synthesis of Pyrrolobenzothiazine and Pyrrolobenzoxazine Ring Systems

A new and simple synthesis of pyrrolobanzothiazine and pyrrolobenzoxazine ring systems is described.Thus, 2-aminophenol and 2-aminothiophenol reacted with maleic anhydride at room temperature to give the acid 7 which were converted into their acid chlorid

Synthesis and characterization of cobalt(II), nickel(II), copper(II) and palladium(II) complexes of polydentate ligands

A few complexes of Co(II), Ni(II), Cu(II) and Pd(II) with a tetradentate ligand N,N'-ethylene-bis-(3-carboxypropenamide) and a bidentate ligand benz--2-carboxymethyl-1,3,4-thiolactam have been synthesised and characterized by elemental analyses, conductance, thermal, magnetic and IR, NMR and electronic spectral studies.

Regioselective reactions of o-aminothiophenol with unsymmetrical maleic anhydrides

Maleic anhydride (MA; Ia) and its methyl (MMA; Ib), dimethyl (DMMa; Ic), phenyl (PMA; Id) and phenylmethyl (PMMA; Ie) derivatives react with o-aminothiophenol (o-ATP) to yield benzothiazines (IIIa-e) via Michael-type addition.In contrast, its oxygenated derivatives react with o-ATP to furnish benzothiazoles (IVf-h) apparently by a different pathway.

The Synthesis of (3'-Oxo-3',4'-dihydro-2'H-1',4'-benzothiazin-2'-yl)acetic Acid and (3'-Oxo-3',4'-dihydro-2'H-1',4'-benzoxazin-2'-yl)acetic Acid Derivatives

Reaction of o-aminophenol with various maleic anhydrides gave first 2-hydroxymaleanilic acids (4-(2'-hydroxyphenylamino)-4-oxobut-2-enoic acids) (1), which were then converted into the 3-oxo-1,4-benzoxazines (1d-h) and (3f-l) under mild basic conditions:

Reactions of Cyclic Anhydrides: Part VIII - Formation of 2-Oxobenzothazines from o-Aminothiophenol and Maleic Anhydride Derivatives

Reaction of o-aminothiophenol (o-ATP) with maleic anhydride, maleic acid or fumaric acid furnishes 2-(oxobenzothiazinyl)acetic acid (Ia); with methyl hydrogenmaleate or methyl hydrogenfumarate, a mixture of Ia and its methyl ester Ib (80 : 20 and 65 : 35