1346261-55-9Relevant academic research and scientific papers
Diastereoselective aziridination of 2-B(pin)-substituted allylic alcohols: An efficient approach to novel organoboron compounds
Hernandez-Toribio, Jorge,Hussain, Mahmud M.,Cheng, Kevin,Carroll, Patrick J.,Walsh, Patrick J.
, p. 6094 - 6097 (2011)
We report that 2-B(pin)-substituted allylic alcohols are good substrates for diastereoselective aziridinations in the presence of PhI(OAc)2 and N-aminophthalimide. Under the aziridination conditions, the valuable B-C bond remains intact, affording a variety of novel boron-substituted aziridines in good yields and excellent diastereoselectivities. Oxidation of the aziridine B-C bond enables generation of syn-1,3-aminohydroxy-2-ketones with high diastereoselectivity.
