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Upstream product

• 38435-51-7 N-hydroxy-4-methoxy-benzenecarboximidoyl chloride 
• 31208-53-4 4-p-tolylbut-3-yn-1-ol 
• 15500-73-9 4-methoxybenzonitrile oxide 
• 624-31-7 4-tolyl iodide 
• 3717-21-3 p-methoxyl benzaldoxime 

Relevant academic research and scientific papers

N-Heterocyclic carbene-catalyzed 1,3-dipolar cycloaddition reactions: A facile synthesis of 3,5-di- and 3,4,5-trisubstituted isoxazoles

A first example of organo-N-heterocyclic carbene (NHC) catalyzed click-type fast 1,3-dipolar cycloaddition of nitrile oxides with alkynes was developed for the regioselective synthesis of 3,5-di- and 3,4,5-trisubstituted isoxazoles. Triethylamine (Et