134659-97-5

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 2873-29-2 D-glucal triacetate 
• 158497-86-0 (2R,3S,E)-3-hydroxy-2,6-bis(tetrahydropyranyloxy)-4-hexenyl p-toluenesulfonate 
• 158497-84-8 (2R,3S,E)-2,6-bis(tetrahydropyranyloxy)-4-hexen-1,3-diol 1,3-diacetate 
• 158497-87-1 (2R,3S,E)-2,3,6-trihydroxy-4-hexenyl p-toluene-sulfonate 
• 158497-85-9 (2R,3S,E)-2,6-bis(tetrahydropyranyloxy)-4-hexen-1,3-diol 
• 158497-88-2 (4S,5R,E)-5,6-epoxy-2-hexen-1,4-diol 
• 134659-95-3 (4S,5R,E)-5,6-epoxy-1,4-bis(tetrahydropyranyloxy)-2-hexen 
• 38081-33-3 (2R,3S,E)-4-hexen-1,2,3,6-tetraol 1,3-diacetate 
• 29581-05-3 (2E,4S,5R)-4,6-diacetoxy-5-hydroxy-2(E)-hexenal 
• 134659-96-4 (2R,3S,E)-3,6-bis(tetrahydropyranyloxy)-4-hexen-2-ol 
• 65-85-0 benzoic acid 
• 134659-91-9 Acetic acid (E)-(1R,2S)-2-acetoxy-1-acetoxymethyl-5-(tetrahydro-pyran-2-yloxy)-pent-3-enyl ester 
• 134659-90-8 Acetic acid (E)-(S)-1-((R)-1,2-diacetoxy-ethyl)-4-hydroxy-but-2-enyl ester 

Relevant academic research and scientific papers

Total Synthesis of Natural (+)-Phomopsolide B, an Antifeedant against Elm Bark Beetle

The total synthesis of natural (+)-phomopsolid B (2) is described.A 5,6-dihydro-2H-pyran-2-one framework was constructed by coupling chiral aldehyde 4 and 4-oxygenated enaminoester 5.The resulting 5,6-dihydro-4-pyrrolidyl-2H-pyran-2-one (3) was converted to natural (+)-phomopsolide B (2) in several steps.