13466-31-4

Upstream product

• 98-86-2 acetophenone 
• 60-34-4 methylhydrazine 
• 6077-10-7 bis(phenylethynyl)mercury 
• 103-71-9 phenyl isocyanate 
• 536-74-3 phenylacetylene 

Downstream Products

• 3240-18-4 α-Phenylaethyl-α-d-azomethan 
• 40093-34-3 C₁₃H₁₉N₃O 
• 40093-30-9 C₁₄H₂₁N₃O 
• 76291-34-4 N-[1-{N-Methyl-N'-[1-phenyl-eth-(E)-ylidene]-hydrazino}-meth-(E)-ylidene]-methanesulfonamide 
• 76291-45-7 4-Methyl-N-[1-{N-methyl-N'-[1-phenyl-eth-(Z)-ylidene]-hydrazino}-meth-(E)-ylidene]-benzenesulfonamide 
• 135676-65-2 C₁₈H₂₀N₄O 
• 135676-93-6 2,6-Dimethyl-5,6-diphenyl-1,2,5,6-tetrahydro-[1,2,4,5]tetrazine-3-carboxylic acid methyl ester 
• 95642-86-7 C₁₁H₁₅N₃ 
• 3240-17-3 (α-Phenyl-aethylazo)-methan 
• 3463-26-1 1-methyl-3-phenyl-1H-pyrazole 
• 128364-63-6 (1-Methoxy-1-phenyl-ethyl)-methyl-diazene 
• 1621003-27-7 (3R,4R,5R)-1,3-dimethyl-4-nitro-3,5-diphenylpyrazolidine 
• 1351960-16-1 (S)-2-dibenzylamino-propionic-N-phenylethylidene-N'-methylhydrazine 

Relevant academic research and scientific papers

TEMPO-mediated Aza-diels-alder reaction: Synthesis of tetrahydropyridazines using ketohydrazones and olefins

A novel, facile, and efficient method for the synthesis of tetrahydropyridazines by a one-pot tandem reaction of easily accessible ketohydrazones and olefins in the presence of 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) has been successfully developed. The reaction involves the initial generation of azoalkenes from direct oxidative dehydrogenation of ketohydrazones using TEMPO as the commercially available oxidant, followed by a subsequent aza-Diels-Alder reaction with olefins.

Catalytic asymmetric synthesis of 4-nitropyrazolidines: An access to optically active 1,2,3-triamines

The first catalytic enantio- and diastereoselective synthesis of 4-nitropyrazolidines is presented. Asymmetric hydrogen-bonding activation of nitro-olefins facilitated the 1,3-dipolar cycloaddition with hydrazones, affording optically active 4-nitropyrazo

Synthesis of a new class of bis(thiourea)hydrazide pseudopeptides as potential inhibitors of β-sheet aggregation

The modular synthesis of a novel pseudopeptide scaffold based on a bis(thiourea)hydrazide motif is reported. This compound class is designed to display "amphifinity", i.e. association with a peptide strand on one but not the other face of the scaffold, and hence could potentially inhibit β-sheet aggregation.

Rh(I) and Ir(I) catalysed intermolecular hydroamination with substituted hydrazines

The catalysed intermolecular hydroamination of a series of terminal alkynes with substituted hydrazines was achieved using Rh(i) and Ir(i) complexes.

Intermolecular Cope-type hydroamination of alkynes using hydrazines

Metal-free, intermolecular hydroaminations are performed upon heating aryl acetylenes and MeNHNH2 at 140°C, with preferential formation of the linear, "anti-Markovnikov" hydrazones. The Royal Society of Chemistry.

Cytotoxicity of 2-ethenyl-2,3-dihydrophthalazine-1,4-diones in murine and human tumor cultured cells

2-Ethenyl-2,3-dihydrophthalazine-1,4-diones were successfully synthesized and proved to be effective cytotoxic agents against the growth of suspended murine and human leukemias and lymphomas. Selected compounds were also active in human HeLa uterine carci

N-Alkenyl-3,5-Pyrazolidinediones from Ketone Hydrazones, PCl3 and Malonic acid.

The title compounds 3, a new series of 3,5-pyrazolidinediones, have been synthesized at room temperature by a one-pot reaction between ketone hydrazone 1, PCl3 and malonic acid.Changing the order of addition of reagents, or their simultaneous addition, gave identical results.In all the procedures the yields are good and in the cases a,b,c and g the E-alkenyl isomer was obtained as the exclusive isomer.A dual mechanism which depends on the order of addition of the reactants is hypothesised.

Hydrazinomercuriation of Terminal Alkynes and 3-Alken-1-ynes. Syntheses of Hydrazones and 1-Amino-1-aza-1,3-dienes

Although hydrazines cannot be directly added to non-activated, terminal acetylenes in the presence of mercury(II) salts, this difficulty was circumvented by treating hydrazines with 1-alkynylmercury trifluoroacetates (2); in this way, several hydrazones (4a-h) and 1-amino-1-aza-1,3-dienes (4i-m) were easily prepared.