1346680-08-7

Upstream product

• 104315-07-3 (E)-ethyl 3-(4-(benzyloxy)phenyl)acrylate 
• 123-08-0 4-hydroxy-benzaldehyde 
• 100-39-0 benzyl bromide 
• 1346680-03-2 (2S,3R)-ethyl 3-((4S,5S)-5-(4-(benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(benzyloxycarbonylamino)-3-hydroxypropanoate 
• 1346679-99-9 (2S,3R)-ethyl 2-azido-3-((4S,5S)-5-(4-(benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-3-hydroxypropanoate 
• 1346679-89-7 (2S,3S)-ethyl 3-((4S,5S)-5-(4-(benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,3-dihydroxypropanoate 
• 1346679-84-2 (E)-ethyl 3-((4S,5S)-5-(4-(benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate 
• 1346679-78-4 ((4S,5S)-5-(4-(benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methanol 
• 1346679-74-0 (4R,5S)-ethyl 5-(4-(benzyloxy)phenyl)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 4397-53-9 p-benzyloxybenzaldehyde 

Downstream Products

• 188744-98-1 (2R,3R,4R,5R)-4-(hydroxy)-2-(hydroxymethyl)-5-(4-hydroxyphenyl)pyrrolidin-3-ol 
• 1346680-14-5 (2R,3R,4R,5R)-benzyl 2-(4-(benzyloxy)phenyl)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 1346680-20-3 (2S,3R,4R,5R)-benzyl 2-(4-(benzyloxy)phenyl)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 1346680-25-8 (1S,2R,3R,4R)-1-(4-(benzyloxy)phenyl)-4-(benzyloxycarbonylamino)pentane-1,2,3,5-tetrayl tetraacetate 
• 1346680-28-1 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(4-(benzyloxy)phenyl)-1-(benzyl-oxycarbonyl)pyrrolidine-3,4-diyl diacetate 
• 1346680-31-6 (5R,6R,7R,7αR)-5-(4-(benzyloxy)phenyl)-6,7-dihydroxytetrahydropyrrolo[1,2-c]oxazol-3(1H)-one 
• 1346680-33-8 (5R,6R,7R,7aR)-6,7-dihydroxy-5-(4-hydroxyphenyl)tetrahydropyrrolo[1,2-c]oxazol-3(1H)-one 

Relevant academic research and scientific papers

Total synthesis of radicamine B and 5-epi-radicamine B

Radicamine B 5 was synthesized from p-hydroxy benzaldehyde 7 stereoselectively using acid catalysed amido cyclisation with the help of neighbouring group participation (NGP). Without NGP both radicamine B 5 and its epimer 5-epi radicamine B 6 were obtaine