188744-98-1

Basic information

• Product Name: 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-5-(4-hydroxyphenyl)-, (2R,3R,4S,5S)-
• Synonyms: 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-5-(4-hydroxyphenyl)-, (2R,3R,4S,5S)-
• CAS NO: 188744-98-1
• Molecular Formula: C11H15 N O4
• Molecular Weight: 0
• Mol File: 188744-98-1.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-5-(4-hydroxyphenyl)-, (2R,3R,4S,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-5-(4-hydroxyphenyl)-, (2R,3R,4S,5S)-(188744-98-1)
• EPA Substance Registry System: 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-5-(4-hydroxyphenyl)-, (2R,3R,4S,5S)-(188744-98-1)

Safety Data

• Hazardous Substances Data: 188744-98-1(Hazardous Substances Data)

Upstream product

• 904893-28-3 (2S,3S,4S,5S)-2-benzyloxymethyl-3,4-dibenzyloxy-5-(4-benzyloxyphenyl)-N-hydroxy-pyrrolidine 
• 188744-86-7 (3aR,4R,6S,6aS)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-6-[4-(tert-butyl-diphenyl-silanyloxy)-phenyl]-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole 
• 120186-59-6 (4-(benzyloxy)phenyl)magnesium bromide 
• 155931-84-3 (2S,3R,4R)-2,3,5-tri-O-benzyl-4-O-formyl-pentanal 
• 1063685-03-9 tert-butyl (4R)-4-[(1R,2S)-1,2-bis(benzyloxy)-3-(4-benzyloxyphenyl)-3-oxopropyl]-2,2-dimethyloxazolidine-3-carboxylate 
• 537030-19-6 (2R,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-3,4-dihydro-2H-pyrrole 1-oxide 
• 1000612-76-9 (2R,3R,4R,5R)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-5-[4-(benzyloxy)phenyl]pyrrolidine 
• 201290-06-4 3,4,6-tri-O-benzyl-1,2-dideoxy-D-xylo-hex-1-enitol 
• 16838-89-4 2,3,5-tri-O-benzyl-D-xylofuranose 
• 6793-92-6 p-benzyloxyphenylbromide 
• 913365-64-7 (2S,3S,4S)-2,3,5-Tris-benzyloxy-4-hydroxy-pentanal oxime 
• 96192-07-3 2,3,5-tri-O-benzyl-L-arabinofuranose 
• 913365-65-8 C₃₂H₄₂INO₄Si 
• 904893-22-7 (2S,3S,4S)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-3,4-dihydro-2H-pyrrole-1-oxide 

Relevant articles and documents

Synthesis of di- and trihydroxy proline derivatives from D-glycals: Application in the synthesis of polysubstituted pyrrolizidines and bioactive 1C-aryl/alkyl pyrrolidines

Six different types of O-benzyl protected proline derivatives have been synthesized from D-glycals and 2C-formyl-glycals. One of the di-O-benzyl protected proline derivatives has been utilized for the synthesis of polysubstituted pyrrolizidines via [3 + 2

An easy route to synthetic analogues of radicamine B, codonopsine and codonopsinine from d-mannitol

A general strategy for the synthesis of analogues of radicamine B has been carried out from d-mannitol. This method has been further extended to the synthesis of analogues of codonopsine and codonopsinine using appropriate Grignard reagents. The hence obtained molecules have been tested against various commercially available glycosidases and found to act as moderate to good inhibitors. This journal is the Partner Organisations 2014.

Total synthesis of radicamine B and 5-epi-radicamine B

Radicamine B 5 was synthesized from p-hydroxy benzaldehyde 7 stereoselectively using acid catalysed amido cyclisation with the help of neighbouring group participation (NGP). Without NGP both radicamine B 5 and its epimer 5-epi radicamine B 6 were obtaine