1346818-42-5

Basic information

• Product Name: 6-chloro-4-[(R)-1-(5-fluoro-2-methoxyphenyl)ethoxy]pyridazin-3-ylamine
• Synonyms: 6-chloro-4-[(R)-1-(5-fluoro-2-methoxyphenyl)ethoxy]pyridazin-3-ylamine
• CAS NO: 1346818-42-5
• Molecular Weight: 297.717
• Mol File: 1346818-42-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-4-[(R)-1-(5-fluoro-2-methoxyphenyl)ethoxy]pyridazin-3-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-4-[(R)-1-(5-fluoro-2-methoxyphenyl)ethoxy]pyridazin-3-ylamine(1346818-42-5)
• EPA Substance Registry System: 6-chloro-4-[(R)-1-(5-fluoro-2-methoxyphenyl)ethoxy]pyridazin-3-ylamine(1346818-42-5)

Safety Data

• Hazardous Substances Data: 1346818-42-5(Hazardous Substances Data)

Upstream product

• 445-82-9 1-(5-fluoro-2-methoxyphenyl)ethanone 
• 446273-59-2 4-bromo-6-chloro-3-pyridazineamine 
• 1346818-41-4 (R)-1-(5-fluoro-2-methoxyphenyl)ethanol 

Relevant articles and documents

HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISEASES

The invention relates to compounds of Formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases in which ALK protein is involved or in which inhibition of ALK activity may induce benefit, especially for the treatment of cancer mediated by a mutated EML4-ALK fusion protein.