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3,5-Diiodopyridin-2-ol, also known as diiodohydroxy pyridine, is a chemical compound characterized by the molecular formula C5H2I2NO. It presents as a white to off-white solid with a melting point around 196-198°C. 3,5-Diiodopyridin-2-ol is recognized for its strong halogen bonding ability, making it a valuable asset in the realms of medicinal and material chemistry research. Its utility in organic synthesis, particularly for the preparation of pharmaceutical compounds, specialty chemicals, and as a building block for complex molecules, underscores its importance in the scientific community. However, due to its toxic nature upon ingestion or inhalation, and its potential to cause skin and eye irritation, careful handling is paramount.

13472-80-5

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13472-80-5 Usage

Uses

Used in Organic Synthesis:
3,5-Diiodopyridin-2-ol is used as a reagent in organic synthesis for its ability to facilitate the creation of various pharmaceutical compounds. Its strong halogen bonding capability makes it a key component in the synthesis process, contributing to the development of new and innovative medications.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 3,5-Diiodopyridin-2-ol is utilized as a precursor in the preparation of specific drugs. Its role in the synthesis of these compounds is critical, as it can influence the effectiveness and properties of the final product.
Used in Specialty Chemicals Production:
3,5-Diiodopyridin-2-ol also serves as a building block for the production of specialty chemicals. Its unique properties allow it to be incorporated into more complex molecules, enhancing the performance and characteristics of these chemicals for specific applications.
Used in Medicinal Chemistry Research:
As a valuable tool in medicinal chemistry, 3,5-Diiodopyridin-2-ol is used in research to explore its potential applications and interactions with biological systems. Its strong halogen bonding ability is of particular interest, as it can provide insights into the design of new drugs and therapeutic agents.
Used in Material Chemistry Research:
In material chemistry, 3,5-Diiodopyridin-2-ol is employed to study its potential in creating new materials with unique properties. Its involvement in the development of these materials can lead to advancements in various industries, including electronics, textiles, and coatings.

Check Digit Verification of cas no

The CAS Registry Mumber 13472-80-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,4,7 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13472-80:
(7*1)+(6*3)+(5*4)+(4*7)+(3*2)+(2*8)+(1*0)=95
95 % 10 = 5
So 13472-80-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H3I2NO/c6-3-1-4(7)5(9)8-2-3/h1-2H,(H,8,9)

13472-80-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,5-diiodo-1H-pyridin-2-one

1.2 Other means of identification

Product number -
Other names 2(1H)-Pyridone, 3,5-diiodo-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13472-80-5 SDS

13472-80-5Relevant academic research and scientific papers

The regioselective iodination of quinolines, quinolones, pyridones, pyridines and uracil

Dutta, Uttam,Deb, Arghya,Lupton, David W.,Maiti, Debabrata

supporting information, p. 17744 - 17747 (2015/12/18)

A radical based direct C-H iodination protocol for quinolines, quinolones, pyridones, pyridines, and uracil has been developed. The iodination occurs in a C3 selective manner for quinolines and quinolones. Pyridones and pyridines undergo C3 and C5 iodination, while dimethyl uracil undergoes C5 iodination. Scope of the method was demonstrated through the rapid synthesis of both electron rich as well as electron poor heteroaromatic iodides. The protocol was found to be scalable and general, while a mechanism has been proposed.

Total Synthesis of Isodesmosine by Stepwise, Regioselective Negishi and Sonogashira Cross-Coupling Reactions

Koseki, Yohei,Sugimura, Takanori,Ogawa, Keita,Suzuki, Rina,Yamada, Haruka,Suzuki, Noriyuki,Masuyama, Yoshiro,Lin, Yong Y.,Usuki, Toyonobu

, p. 4024 - 4032 (2015/06/30)

Isodesmosine is a crosslinking pyridinium amino acid of elastin and is an attractive biomarker for the diagnosis of chronic obstructive pulmonary disease (COPD). In this paper, we describe the total synthesis of isodesmosine. The key features of this synt

Halogenation of pyridinols using bis(sym-collidine)iodine(I) and bis(sym-collidine)bromine(I) hexafluorophosphate

Rousseau, Gerard,Robin, Sylvie

, p. 2467 - 2470 (2007/10/03)

Iodination and bromination of pyridinols was achieved by action of the title reagents in methylene chloride.

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