13472-80-5 Usage
General Description
3,5-Diiodopyridin-2-ol, also known as diiodohydroxy pyridine, is a chemical compound with the molecular formula C5H2I2NO. It is a white to off-white solid with a melting point of approximately 196-198°C. 3,5-Diiodopyridin-2-ol is primarily used as a reagent in organic synthesis, particularly in the preparation of various pharmaceutical compounds. It is also utilized in the production of specialty chemicals and as a building block for more complex molecules. The compound is known for its strong halogen bonding ability and is considered a valuable tool in medicinal and material chemistry research. However, it is important to handle this compound with care, as it is toxic if swallowed or inhaled and can cause skin and eye irritation.
Check Digit Verification of cas no
The CAS Registry Mumber 13472-80-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,4,7 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13472-80:
(7*1)+(6*3)+(5*4)+(4*7)+(3*2)+(2*8)+(1*0)=95
95 % 10 = 5
So 13472-80-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H3I2NO/c6-3-1-4(7)5(9)8-2-3/h1-2H,(H,8,9)
13472-80-5Relevant articles and documents
The regioselective iodination of quinolines, quinolones, pyridones, pyridines and uracil
Dutta, Uttam,Deb, Arghya,Lupton, David W.,Maiti, Debabrata
supporting information, p. 17744 - 17747 (2015/12/18)
A radical based direct C-H iodination protocol for quinolines, quinolones, pyridones, pyridines, and uracil has been developed. The iodination occurs in a C3 selective manner for quinolines and quinolones. Pyridones and pyridines undergo C3 and C5 iodination, while dimethyl uracil undergoes C5 iodination. Scope of the method was demonstrated through the rapid synthesis of both electron rich as well as electron poor heteroaromatic iodides. The protocol was found to be scalable and general, while a mechanism has been proposed.
Halogenation of pyridinols using bis(sym-collidine)iodine(I) and bis(sym-collidine)bromine(I) hexafluorophosphate
Rousseau, Gerard,Robin, Sylvie
, p. 2467 - 2470 (2007/10/03)
Iodination and bromination of pyridinols was achieved by action of the title reagents in methylene chloride.