13473-50-2

Upstream product

• 123-91-1 1,4-dioxane 
• 481-06-1 santonin 
• 64-17-5 ethanol 
• 110-86-1 pyridine 
• 102881-36-7 (3aS)-6t-bromo-3c,6c,6a-trimethyl-(3ar,6at,9bt)-3,3a,4,5,6,6a,8,9b-octahydro-azuleno[4,5-b]furan-2,7-dione 
• 467-42-5 (S)-2-((8aR)-4t-hydroxy-8,8a-dimethyl-1-oxo-(8ar)-4,5,6,7,8,8a-hexahydro-1H-3at,8t-cyclo-azulen-5c-yl)-propionic acid 

Downstream Products

• 1618-98-0 (11S)-10α-hydroxy-30-oxoguaia-4-eno-12,6α-lactone 
• 64-18-6 formic acid 

Relevant academic research and scientific papers

A photocatalyzed aliphatic fluorination

We disclose a new approach to the catalysis of alkane fluorination employing ultraviolet light and a photosensitizer, 1,2,4,5-tetracyanobenzene (TCB). The process is efficient, mild, and operationally straightforward. We demonstrate reaction utility on a variety of substrates, from simple hydrocarbons to complex natural products. In a showcase example, we establish that the well-known photochemical rearrangement of α-santonin can be supplanted by a highly selective catalyzed fluorination. The Royal Society of Chemistry 2014.

Transformation of α-Santonin to Lumisantonin by Pseudomonas cichorii S

Lumisantonin (2) has been identified as one of the transformation products of α-santonin (1) by Pseudomonas cichorii S.