134745-89-4

Upstream product

• 89651-11-6 (3β,8α,9α)-2,3-Dihydro-8-hydroxymethyl-1-<(4-methoxyphenyl)sulfonyl>-6-methylergolin-9-ol 
• 124-63-0 methanesulfonyl chloride 
• 89651-11-6 (3α,8α,9α,10α)-2,3-Dihydro-8-hydroxymethyl-1-<(4-methoxyphenyl)sulfonyl>-6-methylergolin-9-ol 
• 89651-07-0 (3aβ,5aα,6aα,11bα,11cβ)-5,5a,6,6a,7,8,11b,11c-Octahydro-8-<(4-methoxyphenyl)sulfonyl>-5-methylfuro<4,3-fg>quinolin-4(3aH)-one 
• 89651-05-8 1-<(4-Methoxyphenyl)sulfonyl>-1,2,2a,3-tetrahydrobenzindol-4(5H)-one 
• 134745-87-2 4,5-Epoxy-1,2,2a,3,4,5-hexahydro-1-<(4-methoxyphenyl)sulfonyl>benzindole 
• 134745-86-1 1-<(4-Methoxyphenyl)sulfonyl>-1,2,2a,3-tetrahydrobenzindole 
• 124465-55-0 1-benzoyl-1,2,2a,3-tetrahydro-benz[cd]indole 
• 89651-06-9 N-<1-<(4-Methoxyphenyl)sulfonyl>-1,2,2a,3-tetrahydrobenzindol-4-yl>-N-methyl-3-furancarboxamide 
• 89651-07-0 (3aβ,5aβ,6aβ,11bα,11cβ)-5,5a,6,6a,7,8,11b,11c-Octahydro-8-<(4-methoxyphenyl)sulfonyl>-5-methylfuro<4,3-fg>quinolin-4(3aH)-one 

Downstream Products

• 89651-12-7 (3β)-9,10-Didehydro-2,3-dihydro-1-<(4-methoxyphenyl)sulfonyl>-6-methyl-8-methyleneergoline 
• 548-42-5 (+/-)-Agroclavine 
• 95586-10-0 (+/-)-Agroclavine I 

Relevant academic research and scientific papers

A TOTAL SYNTHESIS OF (+/-)-LYSERGENE AND (+/-)-AGROCLAVINE

A preliminary study on the exploitation of a general synthetic route to the ergoline group of alkaloids on the despyrrole analogs was succesfully extended to the first total synthesis of racemic lysergene and agroclavine via the route involving reductive photocyclization of the furylenamide (10) followed by ring opening of the resulting dihydrofuran ring (11).