134767-72-9

Basic information

• Product Name: 2-(phenoxymethyl)-1H-benzo[d]imidazole-5-carboxylic acid
• Synonyms: 2-(phenoxymethyl)-1H-benzo[d]imidazole-5-carboxylic acid
• CAS NO: 134767-72-9
• Molecular Weight: 268.272
• Mol File: 134767-72-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(phenoxymethyl)-1H-benzo[d]imidazole-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenoxymethyl)-1H-benzo[d]imidazole-5-carboxylic acid(134767-72-9)
• EPA Substance Registry System: 2-(phenoxymethyl)-1H-benzo[d]imidazole-5-carboxylic acid(134767-72-9)

Safety Data

• Hazardous Substances Data: 134767-72-9(Hazardous Substances Data)

Upstream product

• 2555-49-9 phenoxyacetic acid ethyl ester 
• 122-59-8 2-phenoxyacetic acid 
• 619-05-6 3,4-diaminobenzoic acid 
• 174533-61-0 4-Amino-3-(2-phenoxy-acetylamino)-benzoic acid methyl ester 
• 701-99-5 Phenoxyacetyl chloride 
• 36692-49-6 Methyl 3,4-diaminobenzoate 
• 37466-90-3 ethyl 3,4-diaminobenzoate 

Downstream Products

• 134767-79-6 2-(phenoxy)methyl-5-<1H>benzimidazole carboxylic acid ethyl ester hydrochloride 
• 902153-11-1 2-Phenoxymethyl-1H-benzoimidazole-5-carbonyl chloride 
• 1415560-91-6 C₂₀H₁₇N₃O₃ 

Relevant articles and documents

Discovery of a novel series of benzimidazole derivatives as diacylglycerol acyltransferase inhibitors

A novel series of benzimidazole derivatives was prepared and evaluated for their diacylglycerol acyltransferase (DGAT) inhibitory activity using microsome from rat liver. Among the newly synthesized compounds, furfurylamine containing benzimidazole carboxamide 10j showed the most potent DGAT inhibitory effect (IC50= 4.4 μM) and inhibited triglyceride formation in HepG2 cells. Furthermore, compound 10j reduced body weight gain of Institute of Cancer Research mice on a high-fat diet and decreased levels of total triglyceride, total cholesterol, and LDL-cholesterol in the blood accompanied with a significant increase in HDL-cholesterol level.

Synthesis and antifungal activity of some new benzimidazole derivatives

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