1347738-32-2

Upstream product

• 762-72-1 allyl-trimethyl-silane 
• 24850-33-7 allyltributylstanane 

Downstream Products

• 1141365-67-4 (3S,4S)-dihydro-4-[2-[(1,1-dimethylethyl)diphenylsilyloxy]ethyl]-3-methyl-2(3H)-furanone 
• 1141365-47-0 2-propenyl (2S,3S,3'aS,4S,5'R)-4-[2-[(1,1-dimethylethyl)diphenylsilyloxy]ethyl]-3',3'a,4,5,5',6'-hexahydro-3-methyl-5'-pentyl-8'-(2-propenyloxy)-spiro[furan-2(3H),2'-[2H]pyrano[2,3,4-de][1]benzopyran]-9'-carboxylate 
• 1182098-75-4 C₃₉H₅₀O₇Si 
• 1333325-54-4 (S)-4-oxo-4-((R)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl)-2-(2-oxoethyl)but-1-yl acetate 
• 1333325-55-5 (S)-2-(2-hydroxyethyl)-4-oxo-4-((R)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl)but-1-yl acetate 
• 1333325-46-4 (S)-2-(2-tert-butyldiphenylsilyloxyethyl)-4-oxo-4-((R)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl)but-1-yl acetate 
• 1333325-47-5 (4S)-4-(2-tert-butyldiphenylsilyloxyethyl)dihydrofuran-2(3H)-one 
• 1333325-48-6 dimethyl ((3S,4S)-4-(2-tert-butyldiphenylsilyloxyethyl)-2-hydroxy-3-methyltetrahydrofuran-2-yl)methylphosphonate 
• 1333325-30-6 (3S,4S)-dimethyl (4-(tert-butyldimethylsilyloxy)methyl-6-tert-butyldiphenylsilyloxy-3-methyl-2-oxohexyl)phosphonate 
• 1333325-49-7 (3S,4S)-4-(2-tert-butyldiphenylsilyloxyethyl)-2,3-dimethyltetrahydrofuran-2-ol 
• 1347738-35-5 (R)-3-((2R,3S)-3-((benzyloxy)methyl)-2-methylhex-5-enoyl)-4-phenyl-1,3-oxazolidin-2-one 
• 1347738-60-6 dimethyl ((3S,4S)-4-((1,3-dioxolan-2-yl)methyl)-5-(benzyloxy)-3-methyl-2-oxopent-1-yl)phosphonate 
• 1347738-56-0 (2R,3S)-methyl 3-((1,3-dioxolan-2-yl)methyl)-4-(benzyloxy)-2-methylbutanoate 
• 1347738-54-8 (2S,3S)-methyl 3-((benzyloxy)methyl)-2-methylhex-5-enoate 

Relevant academic research and scientific papers

Formal synthesis of berkelic acid: A lesson in α-alkylation chemistry

The full details of our enantioselective formal synthesis of the biologically active natural product berkelic acid are described. The insertion of the C-18 methyl group proved challenging, with three different approaches investigated to install the correc