134878-46-9

Basic information

• Product Name: Methyl-3α-benzyloxy-5percentb-cholan-24-oate
• Synonyms: Methyl-3α-benzyloxy-5percentb-cholan-24-oate
• CAS NO: 134878-46-9
• Molecular Weight: 480.731
• Mol File: 134878-46-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Methyl-3α-benzyloxy-5percentb-cholan-24-oate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl-3α-benzyloxy-5percentb-cholan-24-oate(134878-46-9)
• EPA Substance Registry System: Methyl-3α-benzyloxy-5percentb-cholan-24-oate(134878-46-9)

Safety Data

• Hazardous Substances Data: 134878-46-9(Hazardous Substances Data)

Upstream product

• 1249-75-8 methyl lithocholate 
• 100-39-0 benzyl bromide 
• 917-64-6 methyl magnesium iodide 
• 134878-47-0 2'-(3α-Benzyloxy-24-norcholan-23-yl)-4',4'-dimethyl-4',5'-dihydrooxazole 
• 100-44-7 benzyl chloride 
• 80724-92-1 2'-(3α-Hydroxy-24-norcholan-23-yl)-4',4'-dimethyl-4',5'-dihydrooxazole 
• 434-13-9 Lithocholic acid 

Downstream Products

• 142972-60-9 3-benzyl lithocholic acid 
• 145640-82-0 methyl-(3α-benzyloxy-24-norcholan-23-yl)-triphenylphosphonium bromide 
• 145640-83-1 4'-(3α-benzyloxychol-24-en)-2',2',6',6'-tetramethylpiperidine-1'-oxyl 
• 145476-18-2 3α-benzyloxy-24-bromocholane 
• 145476-17-1 3α-benzyloxycholan-24-ol 

Relevant articles and documents

CHOLESTEROL/BILE ACID/BILE ACID DERIVATIVE-MODIFIED THERAPEUTIC ANTI-CANCER DRUGS

Cholesterol-modified anti-cancer therapeutic drug compounds, bile-acid-modified anti-cancer therapeutic drug compounds, and bile-acid-derivative-modified anti-cancer therapeutic drug compounds; emulsion, microemulsion, and micelle formulations that include the compounds, methods for administering the compounds and formulations; and methods for treating cancer using the compounds and formulations.

On the protection of 3α-hydroxy group of A/B cis steroids

The difficulties encountered in the protection of 3α-hydroxy group of lithocholic acid 1 with three different types of protective groups are described. Only benzyl ether derivative was found to be suitable for synthetic transformations. The methodology for the synthesis of benzyl ethers of A/B cis steroids is reported for the first time.