1349068-06-9Relevant academic research and scientific papers
Preparation of small-molecule microarrays by trans-cyclooctene tetrazine ligation and their application in the high-throughput screening of protein-protein interaction inhibitors of bromodomains
Zhang, Chong-Jing,Tan, Chelsea Y. J.,Ge, Jingyan,Na, Zhenkun,Chen, Grace Y. J.,Uttamchandani, Mahesh,Sun, Hongyan,Yao, Shao Q.
, p. 14060 - 14064 (2013)
Fast and efficient: A library of trans-cyclooctene (TCO)-modified small molecules were immobilized on tetrazine-functionalized glass slides by using the fastest bioorthogonal reaction known. The resulting small-molecule microarray was screened against a variety of human bromodomains to identify protein-protein interaction inhibitors. Copyright
MALE CONTRACEPTIVE COMPOSITIONS AND METHODS OF USE
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Page/Page column 86, (2011/12/02)
The invention relates to compositions and methods for effecting male contraception.
