134915-80-3Relevant academic research and scientific papers
Imidazolines as Amide Bond Replacements
Gilbert, Ian H.,Rees, David C.,Crockett, Alan K.,Jones, Raymond C. F.
, p. 6315 - 6336 (1995)
This work describes the use of a 2,5,5-trisubstituted imidazoline as an amide bond replacement.The replacement is incorporated into dipeptide derivatives of Phe, Trp, Lys and Nle and also into the CCK-4 analogue Trp-Nle-Asp-Phe-NH2 and the pentagastrin an
Amide Bond Replacements: Incorporation of a 2,5,5-Trisubstituted Imidazoline into Dipeptides and into a CCK-4 Derivative.
Gilbert, Ian,Rees, David C.,Richardson, Reginald S.
, p. 2277 - 2280 (2007/10/02)
Synthetic methodology for the introduction of a 2,5,5-trisubstituted imidazoline ring as an amide replacement into dipeptide derivatives of Phe, Trp, Lys(N6-CBZ) and Nle is described.This replacement is also incorporated into the Trp-Nle bond o
