1349191-55-4

Basic information

• Product Name: (S)-ethyl-5-(benzylamino)-6-phenyl-hex-2-ynoate
• Synonyms: (S)-ethyl-5-(benzylamino)-6-phenyl-hex-2-ynoate
• CAS NO: 1349191-55-4
• Molecular Weight: 321.419
• Mol File: 1349191-55-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-ethyl-5-(benzylamino)-6-phenyl-hex-2-ynoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-ethyl-5-(benzylamino)-6-phenyl-hex-2-ynoate(1349191-55-4)
• EPA Substance Registry System: (S)-ethyl-5-(benzylamino)-6-phenyl-hex-2-ynoate(1349191-55-4)

Safety Data

• Hazardous Substances Data: 1349191-55-4(Hazardous Substances Data)

Upstream product

• 42217-00-5 3,3,3-triethoxypropyne 
• 42216-99-9 Triethyl-2,3-dibrom-orthopropanoat 
• 42216-96-6 triethyl orthoacrylate 
• 42216-95-5 2-bromo-1,1,1-triethoxypropane 
• 115-80-0 Triethyl orthopropionate 
• 3182-93-2 (L)-phenylalanine ethyl ester hydrochloride 
• 63-91-2 L-phenylalanine 
• 511286-63-8 (4S) 3,4-dibenzyl[1,2,3]oxathiazolidine-2,2-dioxide 
• 19817-70-0 (S)-ethyl N-benzoyl-phenylalaninate 
• 5267-65-2 (S)-N-(1-hydroxy-3-phenylpropan-2-yl)benzamide 

Relevant articles and documents

Practical synthesis of functionalized terminal alkynes, 3,3,3-triethoxypropyne and ketal protected prop-2-ynones

Practical and economical synthesis of synthetically valuable 3,3,3-triethoxypropyne, ketal protected phenyl and methyl substituents prop-2-ynones is described. Bromination and subsequent 18-crown-6 catalyzed elimination of triethylorthoacrylate and ketal

Reactivity of cyclic sulfamidates towards lithium acetylides: Synthesis of alkynylated amines

A synthetically useful level of reactivity of cyclic sulfamidates toward acetylides is described. Ring-opening reactions of a structurally diverse set of 1,2-and 1,3-cyclic sulfamidates with a range of lithium acetylides from aliphatic, cyclic, aromatic, heteroaromatic, and functionalized alkynes proceed smoothly in a regioselective manner to give the corresponding N-sulfate intermediates. Hydrolysis of these intermediates under acidic conditions furnishes the alkynylated amines in yields ranging from 29% to 98%. The scope of the acetylenic substitution reaction with the structural variations in both the cyclic sulfamidates and alkynes is briefly examined.