134922-57-9

Upstream product

• 16666-81-2 cyclohexyltriphenylphosphorane 
• 112571-70-7 Ethyl 4-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enodialdopyranoside-(1,5) 
• 130316-22-2 <5S-(5α,6β)>-5-<(tert-Butyldimethylsilyl)oxy>-6-(cyclohexylidenemethyl)-5,6-dihydro-2H-pyran-2-one 
• 130335-92-1 Ethyl 4-O-(tert-butyldimethylsilyl)-6-cyclohexylidene-2,3,6-trideoxy-α-D-erythro-hex-2-enoaldopyranoside-(1,5) 
• 134934-18-2 Ethyl 4-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside 
• 3323-72-6 ethyl 4,6-di-O-acetyl-2,3-dideoxy-α-D-erythrohex-2-enopyranoside 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 134948-79-1 Ethyl 4-O-(tert-butyldimethylsilyl)-2,3-dideoxy-6-O-pivaloyl-α-D-erythro-hex-2-enopyranoside 
• 125816-07-1 <5S-(5α,6β)>-5-<(tert-Butyldimethylsilyl)oxy>tetrahydro-6-(cyclohexylmethyl)-2H-pyran-2-one 
• 75-07-0 acetaldehyde 

Downstream Products

• 134922-58-0 Methanesulfonic acid 1-[(5S,6R)-5-(tert-butyl-dimethyl-silanyloxy)-6-cyclohexylmethyl-2-oxo-tetrahydro-pyran-3-yl]-ethyl ester 
• 125816-10-6 <3S-<3α,5β(R^*)>>-5-(2-Cyclohexyl-1-aminoethyl)dihydro-3-isopropyl-2(3H)-furanone 
• 118041-20-6 <3S-<3α,5β(R^*)>>-5-(2-Cyclohexyl-1-azidoethyl)dihydro-3-isopropyl-2(3H)-furanone 
• 125816-09-3 <3S-<3α,5β(S^*)>>-5-(2-Cyclohexyl-1-hydroxyethyl)dihydro-3-isopropyl-2(3H)-furanone 
• 125816-12-8 <3R-(3α,5β,6α)>-5-<(tert-Butyldimethylsilyl)oxy>tetrahydro-6-(cyclohexylmethyl)-3-isopropyl-2H-pyran-2-one 
• 125816-08-2 <3S-(3α,5α,6β)>-5-<(tert-Butyldimethylsilyl)oxy>tetrahydro-6-(cyclohexylmethyl)-3-isopropyl-2H-pyran-2-one 
• 134922-56-8 <3R-<3α,5α(R^*)>>-5-(2-Cyclohexyl-1-azidoethyl)dihydro-3-isopropyl-2(3H)-furanone 
• 134922-54-6 <5S-(5α,6β),3(Z)>-5-<(tert-Butyldimethylsilyl)oxy>tetrahydro-6-(cyclohexylmethyl)-3-ethylidene-2H-pyran-2-one 
• 134922-50-2 <5S-(5α,6β),3(E)>-5-<(tert-Butyldimethylsilyl)oxy>tetrahydro-6-(cyclohexylmethyl)-3-ethylidene-2H-pyran-2-one 
• 134922-55-7 <3R-<3α,5α(S^*)>>-5-(2-Cyclohexyl-1-hydroxyethyl)dihydro-3-isopropyl-2(3H)-furanone 
• 130250-38-3 <3R-<3α,5α(R^*)>>-5-(2-Cyclohexyl-1-aminoethyl)dihydro-3-isopropyl-2(3H)-furanone 
• 134922-51-3 <2S,4S,5S>-6-Cyclohexyl-5-<(N-cyclohexyl-N-methyl)glycyl-3-(1-naphthyl)-L-alanyl-3-(4-thiazolyl)-L-alanyl)amino>-4-hydroxy-2-isopropylhexanoyl-<2-(4-morpholino)ethyl>amide 
• 134922-51-3 <2R,4S,5S>-6-Cyclohexyl-5-<(N-cyclohexyl-N-methyl)glycyl-3-(1-naphthyl)-L-alanyl-3-(4-thiazolyl)-L-alanyl)amino>-4-hydroxy-2-isopropylhexanoyl-<2-(4-morpholino)ethyl>amide 
• 134922-68-2 <3S-<3α,5β(R^*)>>-5-<2-Cyclohexyl-1-(N-cyclohexyl-N-methyl)glycyl-3-(1-naphthyl)-L-alanyl-3-(4-thiazolyl)-L-alanyl)aminoethyl>dihydro-3-isopropyl-2(3H)-furanone 

Relevant academic research and scientific papers

Synthesis of renin inhibitors possessing hydroxyethylene isostere residue from 3,4,6-tri-O-acetyl-D-glucal via lactone precursor

Syntheses of precursors for renin inhibitors possessing hydroxyethylene isostere residue from 2,4,6-tri-O-acetyl-D-glucal via lactone precursor is described . This route makes it possible to synthesize analogues with various substituents at C-2 and C-5 of

SYNTHESIS OF THE LACTONE PRECURSOR TO HYDROXYETHYLENE DIPEPTIDE ISOSTERE FROM 3,4,6-TRI-O-ACETYL-D-GLUCAL

(2S,4S,5S)-5-Amino-6-cyclohexyl-4-hydroxy-2-isopropyl hexanoic acid lactone (5) was synthesized from 3,4,6-tri-O-acetyl-D-glucal in an efficient manner.