134931-85-4

Upstream product

• 97806-83-2 (S)-2-[(1S,2R,3R)-4-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-1,3-dimethyl-butyl]-6-hydroxy-5,6-dimethyl-6H-pyran-3-one 
• 85828-13-3 (1S,2S,3R,4R)-5-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-1-(4,5-dimethyl-furan-2-yl)-2,4-dimethyl-pentan-1-ol 
• 134860-57-4 (1S,2S,4R)-5-Benzyloxy-1-(4,5-dimethyl-furan-2-yl)-1-hydroxy-2,4-dimethyl-pentan-3-one 
• 52480-43-0 4,5-dimethyl-2-formylfuran 
• 71011-64-8 (2R,3S)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-3-methyl-oxirane 
• 98315-15-2 (2S,3R,4R,5R)-6-Benzyloxy-2,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethyl-hexanal 
• 98315-14-1 (2S,3R,4R,5R)-6-Benzyloxy-2,4-bis-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethyl-hexanenitrile 
• 98315-16-3 2-(1-Bromomethyl-vinyl)-2,5,5-trimethyl-[1,3]dioxane 
• 98315-30-1 2-isopropenyl-2,5,5-trimethyl-1,3-dioxane 
• 98315-18-5 (1R,3S,4S,5R)-3-((S)-2-Benzyloxy-1-methyl-ethyl)-1,4-dimethyl-8-methylene-2,9-dioxa-bicyclo[3.3.1]nonan-6-ol 
• 98315-10-7 (3S,4S,5R)-6-Benzyloxy-4-hydroxy-3,5-dimethyl-hexanenitrile 
• 134860-58-5 (1S,2R,3R,4R)-5-Benzyloxy-1-(4,5-dimethyl-furan-2-yl)-2,4-dimethyl-pentane-1,3-diol 
• 98315-11-8 (2S,3R,4R,5R)-6-Benzyloxy-2,4-dihydroxy-3,5-dimethyl-hexanenitrile 
• 98315-17-4 (5R,6S,7S,8S)-9-Benzyloxy-5,7-bis-(tert-butyl-dimethyl-silanyloxy)-6,8-dimethyl-2-(2,5,5-trimethyl-[1,3]dioxan-2-yl)-non-1-en-4-ol 

Relevant academic research and scientific papers

ASYMMETRIC ALDOL REACTIONS USING CHIRAL BORON REAGENTS: APPLICATION TO THE SYNTHESIS OF TIRANDAMYCIN A

The bicyclic acetal 1, a key intermediate in previous synthetic studies on tirandamycin A, has been prepared in enantiomerically pure form starting from the (R)-ethylketone 2 and the aldehyde 3.A reagent controlled aldol reaction using (-)-(Ipc)2BOTf sele

Synthesis of the dioxabicyclononane unit of tirandamycin

A seven-step synthesis of (±)-3b, an advanced, common intermediated for construction of the dioxabicyclononane units of both tirandamycin and streptolydigin is described. Conversion of 3b to the fully developed fragment of tirandamycin is also reported.