134935-90-3Relevant academic research and scientific papers
Synthesis of 2-Substituted 8-Amino-3-oxoindolizidine-2-carboxylic Acid Derivatives as Peptide Conformation Mimetics
Gonzalez-Muniz, Rosario,Dominguez, Maria Jose,Garcia-Lopez, Maria Teresa
, p. 5191 - 5198 (2007/10/02)
The synthesis of methyl 8-tert-butyloxycarbonylamino-3-oxoindolizidine-2-carboxylate and its alkyl derivatives bearing Phe, Trp and Asp side chains at C2 position are described.These bridged bicyclic lactams, obtained with high and moderate ste
A FACILE SYNTHESIS OF 8-AMINO-3-OXOINDOLIZIDINE DERIVATIVES AS CONFORMATIONALLY RESTRICTED ORNITHYL PSEUDODIPEPTIDES
Gomez-Monterrey, I.,Dominguez, M. J.,Gonzalez-Muniz, R.,Harto, J. R.,Garcia-Lopez, M. T.
, p. 1089 - 1092 (2007/10/02)
One pot procedure for the synthesis of 8-amino-3-oxoindolizidines from Zδ-protected ornithyl ketomethylene pseudodipeptide derivatives is described.This procedure, involving hydrogenolysis of the Z-group, intramolecular reductive amination and
