134964-66-2Relevant academic research and scientific papers
OXIDATIVE ADDITION OF HYDROXIDE ANIONS TO NITROALKENES VIA THE RADICAL ANIONS OF α-NITRO-OXIRANES
Bowman, W. Russel,Brown, David S.,Chaffin, Julie D. E.,Symons, Martyn C. R.,Jackson, Stuart W.,Willcocks, Neil A.
, p. 2285 - 2288 (1991)
Stereoselective oxidative addition of hydroxide anions to nitroalkenes was carried out using potassium ferricyanide to yield α-nitro-oxiranes by a novel non-chain mechanism involving cyclisation of alkoxide anions onto α-nitroalkyl radicals.
Regioselective Opening of Nitroepoxides with Unsymmetrical Diamines
Nosood, Yazdanbakhsh L.,Ziyaei Halimehjani, Azim,González, Florenci V.
, p. 1252 - 1258 (2018/02/09)
Nitroepoxides are easily transformed into benzodiazepines, tetrahydrobenzodiazepines, imidazopyridines, and N-alkyl tetrahydroquinoxalines by treatment with 2-aminobenzylamines, 2-aminopyridines, and N-alkyl 1,2-diaminobenzenes, respectively. Regioselectivity is controlled through attack of the most nucleophilic nitrogen of the unsymmetrical diamine to the β position of the epoxide. These reactions represent an efficient way to prepare privileged bioactive structures.
Preparation of Morpholines and Benzoxazines Starting from Nitroepoxides
Capel,Vidal-Albalat,Rodríguez,González
, p. 2572 - 2580 (2016/08/11)
Nitroepoxides are easily transformed into 2,3-disubstituted morpholines and 2,3-disubstituted benzoxazines in a two-step sequence by treatment with N-methylethanolamine and N-methyl-2-hydroxyaniline, respectively, in a highly stereoselective fashion.
