1350428-79-3Relevant articles and documents
Synthesis and properties of molecular probes for the rescue site on mutant cystic fibrosis transmembrane conductance regulator
Alkhouri, Bashar,Denning, Robert A.,Chiaw, Patrick Kim,Eckford, Paul D.W.,Yu, Wilson,Li, Canhui,Bogojeski, Jovanka J.,Bear, Christine E.,Viirre, Russell D.
, p. 8693 - 8701 (2012/03/09)
Cystic fibrosis is a genetic disease caused by mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. In vitro experiments have demonstrated that 4-methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol (VRT-532, 1) is able t