1350432-15-3Relevant academic research and scientific papers
Sodium hydride-mediated synthesis of 1,5-diaryl-1,2,3-triazoles from anti-3-aryl-2,3-dibromopropanoic acids and organic azides
Cheng, Xue-Zhi,Liu, Wei,Huang, Zhen-Dong,Kuang, Chun-Xiang
, p. 764 - 766 (2013/07/26)
A series of 1,5-disubstituted 1,2,3-triazoles are synthesized by a one-pot process from anti-3-aryl-2,3-dibromopropanoic acids and organic azides mediated by sodium hydride in dimethyl sulfoxide. The reaction is mild and simple, does not require a transition-metal catalyst, and gives products in good to excellent yields.
Synthesis and antimalarial activities of a diverse set of triazole-containing furamidine analogues
Berger, Olivier,Kaniti, Archana,van Ba, Christophe Tran,Vial, Henri,Ward, Stephen A.,Biagini, Giancarlo A.,Bray, Patrick G.,O'Neill, Paul M.
, p. 2094 - 2108 (2012/06/18)
Four different series of triazole diamidines have been prepared by the Pinner method from the corresponding triazole dinitriles. Copper-catalyzed "click chemistry" was used for the synthesis of 1,4- and 4,5-substituted triazoles, aryl magnesium acetylide
