1350454-74-8

Basic information

• Product Name: 1-(2-(4-(6-(3-methoxyphenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-ylamino)ethyl)-3-phenylurea
• Synonyms: 1-(2-(4-(6-(3-methoxyphenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-ylamino)ethyl)-3-phenylurea
• CAS NO: 1350454-74-8
• Molecular Weight: 485.569
• Mol File: 1350454-74-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(2-(4-(6-(3-methoxyphenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-ylamino)ethyl)-3-phenylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(4-(6-(3-methoxyphenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-ylamino)ethyl)-3-phenylurea(1350454-74-8)
• EPA Substance Registry System: 1-(2-(4-(6-(3-methoxyphenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-ylamino)ethyl)-3-phenylurea(1350454-74-8)

Safety Data

• Hazardous Substances Data: 1350454-74-8(Hazardous Substances Data)

Upstream product

• 815596-13-5 6-(3-Methoxyphenyl)-5-(2-(methylthio)pyrimidin-4-yl)imidazo[2,1-b]thiazole 
• 53673-01-1 1-(2-aminoethyl)-3-phenylurea 
• 1261242-10-7 benzyl 2-(3-phenylureido)ethylcarbamate 
• 5000-65-7 2-bromo-3'-methoxyacetophenone 
• 92754-06-8 6-(3-methoxyphenyl)imidazo[2,1-b]thiazole 
• 103-71-9 phenyl isocyanate 

Downstream Products

• 1350454-77-1 1-(2-(4-(6-(3-hydroxyphenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-ylamino)ethyl)-3-phenylurea 

Relevant articles and documents

Imidazothiazole-based potent inhibitors of V600E-B-RAF kinase with promising anti-melanoma activity: biological and computational studies

A series of imidazothiazole derivatives possessing potential activity against melanoma cells were investigated for molecular mechanism of action. The target compounds were tested against V600E-B-RAF and RAF1 kinases. Compound 1zb is the most potent agains