53673-01-1

Upstream product

• 120-93-4 imidazolidone 
• 62-53-3 aniline 
• 103-71-9 phenyl isocyanate 
• 107-15-3 ethylenediamine 
• 1261242-10-7 benzyl 2-(3-phenylureido)ethylcarbamate 

Downstream Products

• 65417-30-3 N-phenyl-N'-[2-(N'-phenyl-thioureido)-ethyl]-urea 
• 56202-83-6 1-[2-(2-Hydroxy-2-phenyl-ethylamino)-ethyl]-3-phenyl-urea 
• 53671-68-4 1-{2-[3-(2-Chloro-phenoxy)-2-hydroxy-propylamino]-ethyl}-3-phenyl-urea 
• 83047-60-3 1-{2-[3-(2-Acetyl-phenoxy)-2-hydroxy-propylamino]-ethyl}-3-phenyl-urea 
• 58027-38-6 1-o-carbamoylphenoxy-3-β-(3-phenylureido)ethylamino-2-propanol 
• 83019-67-4 1-[2-(2-Hydroxy-3-phenoxy-propylamino)-ethyl]-3-phenyl-urea 
• 83019-68-5 1-{2-[2-Hydroxy-3-(2-vinyl-phenoxy)-propylamino]-ethyl}-3-phenyl-urea 
• 58027-88-6 1-(2-ethyl-4-propionamidophenoxy)-3-β-(3-phenylureido)ethylamino-2-propanol 
• 56443-68-6 1-<2-(benzylamino)ethyl>-3-phenylurea 
• 66888-43-5 [2-(3-Phenyl-ureido)-ethyl]-carbamic acid phenyl ester 
• 53671-71-9 1-(2-cyanophenoxy)-3-β-(3-phenylureido)ethylamino-2-propanol 
• 56442-94-5 1-<2-<<2-hydroxy-2-(4-hydroxyphenyl)ethyl>amino>ethyl>-3-phenylurea 
• 58827-59-1 1-{2-[3-(Benzofuran-4-yloxy)-2-hydroxy-propylamino]-ethyl}-3-phenyl-urea 
• 58827-57-9 1-{2-[3-(Benzo[b]thiophen-4-yloxy)-2-hydroxy-propylamino]-ethyl}-3-phenyl-urea 

Relevant academic research and scientific papers

Imidazothiazole-based potent inhibitors of V600E-B-RAF kinase with promising anti-melanoma activity: biological and computational studies

A series of imidazothiazole derivatives possessing potential activity against melanoma cells were investigated for molecular mechanism of action. The target compounds were tested against V600E-B-RAF and RAF1 kinases. Compound 1zb is the most potent agains

Broad-spectrum antiproliferative activity of a series of 6-(4-fluorophenyl)-5-(2-substituted pyrimidin-4-yl)imidazo[2,1-b]thiazole derivatives

This article described the synthesis and in vitro antiproliferative activities a series of 6-(4-fluorophenyl)-5-(2-substituted pyrimidin-4-yl)imidazo[2,1-b]thiazole derivatives. The nine target compounds were tested for in vitro antitumor effect against a

New imidazo[2,1-b]thiazole derivatives: Synthesis, in vitro anticancer evaluation, and in silico studies

A series of 18 new imidazo[2,1-b]thiazole derivatives was synthesized. Their in vitro antiproliferative activities against A375P human melanoma cell line and NCI-60 cell line panel were tested. Compounds 15, 16, 18, 22, 26-28, and 31 showed superior poten

Synthesis of new 6-(4-Fluorophenyl)-5-(2-substituted pyrimidin-4-yl) imidazo[2,1-b] thiazole derivatives and their antiproliferative activity against melanoma cell line

Synthesis of a new series of pyrimidinyl-imidazo[2,1-b]thiazole derivatives is described. Their antiproliferative activity against A375 human melanoma cell line was tested and the effect of substituents on the pyrimidinyl ring side chain was investigated.

SUBSTITUTED-AMINOHYDROXY-PROPOXY-THIADIAZOLES, BETA-BLOCKING COMPOSITIONS AND USE

Novel substituted-aminohydroxypropoxy-thiadiazoles and pharmaceutically acceptable salts thereof exhibit β-adrenergic blocking activity.