1350473-75-4

Upstream product

• 73909-16-7 2-chloro-5-methylanisole 
• 85740-98-3 4-chloro-3-methoxybenzoic acid 
• 615-74-7 2-chloro-5-methylphenol 
• 342435-01-2 1-(4-chloro-3-methoxyphenyl)-2-(pyridin-4-yl)ethanone 
• 116022-18-5 methyl 4-chloro-3-methoxybenzoate 
• 636-98-6 p-nitrobenzene iodide 
• 1350473-74-3 4-(3-(4-chloro-3-methoxyphenyl)-1H-pyrazol-4-yl)pyridine 

Downstream Products

• 1350473-76-5 4-[3-(4-chloro-3-methoxyphenyl)-1-(4-aminophenyl)-1H-pyrazol-4-yl]pyridine 
• 1350473-77-6 1-{4-[3-(4-chloro-3-methoxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}-3-(2,3-dichlorophenyl)urea 
• 1350473-78-7 1-{4-[3-(4-chloro-3-methoxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}-3-(3,4-dichlorophenyl)urea 
• 1350473-79-8 1-{4-[3-(4-chloro-3-methoxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}-3-(4-chloro-3-(trifluoromethyl)phenyl)urea 
• 1350473-80-1 1-{4-[3-(4-chloro-3-methoxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}-3-(3,5-bis(trifluoromethyl)phenyl)urea 
• 1421622-01-6 3,4-dichloro-N-{4-[3-(4-chloro-3-methoxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}benzamide 
• 1350473-82-3 3,5-dichloro-N-{4-[3-(4-chloro-3-methoxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}benzamide 
• 1350473-84-5 4-chloro-3-trifluoromethyl-N-{4-[3-(4-chloro-3-methoxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}benzamide 
• 1350473-86-7 3,5-bis(trifluoromethyl)-N-{4-[3-(4-chloro-3-methoxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}benzamide 
• 1350473-88-9 1-{4-[3-(4-chloro-3-hydroxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}-3-(2,3-dichlorophenyl)urea 
• 1350473-90-3 1-{4-[3-(4-chloro-3-hydroxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}-3-(3,4-dichlorophenyl)urea 
• 1350473-93-6 1-{4-[3-(4-chloro-3-hydroxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}-3-(4-chloro-3-(trifluoromethyl)phenyl)urea 
• 1350473-95-8 1-{4-[3-(4-chloro-3-hydroxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}-3-(3,5-bis(trifluoromethyl)phenyl)urea 
• 1350473-97-0 3,4-dichloro-N-{4-[3-(4-chloro-3-hydroxyphenyl)-4-(pyridin-4-yl)-1H-pyrazol-1-yl]phenyl}benzamide 

Relevant academic research and scientific papers

New diarylureas and diarylamides containing 1,3,4-triarylpyrazole scaffold: Synthesis, antiproliferative evaluation against melanoma cell lines, ERK kinase inhibition, and molecular docking studies

Synthesis of a new series of diarylureas and diarylamides possessing 1,3,4-triarylpyrazole scaffold is described. Their in vitro antiproliferative activities against 9 human melanoma cell lines were tested. Compounds 12, 13, 15, and 21-23 showed the highe