85740-98-3

Basic information

• Product Name: 4-CHLORO-3-METHOXYBENZOIC ACID
• Synonyms: TIMTEC-BB SBB008504;4-CHLORO-3-METHOXYBENZOIC ACID;4-CHLORO-3-METHOXYBENZOIC ACID ---POWDER---;4-Chloro-3-Methoxybenzoic;4-Chloro-3-methoxybenzoic acid, >=98%;Benzoic acid,4-chloro-3-methoxy-
• CAS NO: 85740-98-3
• Molecular Formula: C₈H₇ClO₃
• Molecular Weight: 186.59
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid;Acids & Esters;Anisoles, Alkyloxy Compounds & Phenylacetates;Chlorine Compounds
• Mol File: 85740-98-3.mol
• Article Data: 22

Chemical Properties

• Melting Point: 217.0 to 221.0 °C
• Boiling Point: 325.4 °C at 760 mmHg
• Flash Point: 150.6 °C
• Appearance: /
• Density: 1.352 g/cm³
• Vapor Pressure: 9.44E-05mmHg at 25°C
• Refractive Index: 1.562
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.85±0.10(Predicted)
• CAS DataBase Reference: 4-CHLORO-3-METHOXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-3-METHOXYBENZOIC ACID(85740-98-3)
• EPA Substance Registry System: 4-CHLORO-3-METHOXYBENZOIC ACID(85740-98-3)

Safety Data

• Hazard Codes: T,N
• Statements: 36/37/38-50-25
• Safety Statements: 26-36/37/39-61-45
• RIDADR: 3077
• WGK Germany: 3
• HazardClass: 9
• PackingGroup: Ⅲ
• Hazardous Substances Data: 85740-98-3(Hazardous Substances Data)

Usage

General Description

4-CHLORO-3-METHOXYBENZOIC ACID, also known as 4-Chloro-3-methoxybenzoate, is a chemical compound with the molecular formula C8H7ClO3. It is a white crystalline solid that is insoluble in water but soluble in organic solvents. 4-CHLORO-3-METHOXYBENZOIC ACID is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a building block in the production of dyes and polymers. 4-Chloro-3-methoxybenzoate exhibits antimicrobial properties and is used in the development of antibacterial agents. Additionally, it has potential applications in the production of flavoring agents and fragrances.

InChI:InChI=1/C8H7ClO3/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4H,1H3,(H,10,11)

Upstream product

• 75-93-4 methyl bisulfate 
• 61124-56-9 4'-chloro-3'-hydroxyacetophenone 
• 73909-16-7 2-chloro-5-methylanisole 
• 586-38-9 3-Methoxybenzoic acid 
• 615-74-7 2-chloro-5-methylphenol 
• 74-87-3 methylene chloride 
• 99-06-9 3-Carboxyphenol 
• 13726-17-5 (4-chloro-3-methoxyphenyl)methan-1-ol 

Downstream Products

• 13726-17-5 (4-chloro-3-methoxyphenyl)methan-1-ol 
• 321196-01-4 4-chloro-3-methoxy-benzohydrazide 
• 931409-94-8 3-methoxy-4-chlorobenzoic acid allyl ester 
• 116022-18-5 methyl 4-chloro-3-methoxybenzoate 
• 342435-00-1 4-chloro-N,3-dimethoxy-N-methylbenzamide 
• 1352810-88-8 phenyl 3-(4-chloro-3-methoxyphenyl)-4-(pyridin-4-yl)-1H-pyrazole-1-carboxylate 
• 1352810-87-7 C₂₂H₁₆ClN₃O₃ 
• 1352811-07-4 C₂₀H₂₂ClN₅O₂ 
• 1352811-08-5 C₂₂H₂₆ClN₅O₂ 
• 1352811-09-6 C₂₂H₂₄ClN₅O₃ 
• 1352811-10-9 C₂₄H₂₈ClN₅O₃ 
• 1352811-11-0 C₂₃H₂₇ClN₆O₂ 
• 1352811-12-1 C₂₄H₂₇ClN₆O₃ 
• 1352811-13-2 C₂₃H₂₆ClN₅O₂ 

Relevant articles and documents

Evaluation of the inhibitory effects of pyridylpyrazole derivatives on lps-induced pge2 productions and nitric oxide in murine raw 264.7 macrophages

A series of thirteen triarylpyrazole analogs were investigated as inhibitors of lipopolysaccharide (LPS)-induced prostaglandin E2 (PGE2 ) and nitric oxide (NO) production in RAW 264.7 macrophages. The target compounds 1a–m have first

Design, synthesis, and in vitro antiproliferative and kinase inhibitory effects of pyrimidinylpyrazole derivatives terminating with arylsulfonamido or cyclic sulfamide substituents

A novel series of substituted pyrimidine compounds bearing N-phenylpyrazole and terminating with aryl and cyclic sulfonamido moiety were designed, synthesized, and evaluated in vitro as antiproliferative agents against a panel of 53 cell lines of differen

3-methoxy-4-chlorobenzoic acid and preparation method thereof

The invention discloses 3-methoxy-4-chlorobenzoic acid and a preparation method thereof. The preparation method comprises the following steps: by taking 3-hydroxybenzoic acid as a raw material, firstly halogenating with Cl2, and then directly reacting with monochloromethane for carrying out hydrocarbylation on phenolic hydroxyl group, so that the 3-methoxy-4-chlorobenzoic acid is obtained. The preparation method has the advantages of cheap and available raw materials, simple operation steps, good substituent group location capacity, high product purity and high yield, can be applicable to large-scale industrial production and can produce relatively high economic benefit.