135049-84-2

Basic information

• Product Name: 2-chloro-4-iodobenzyl bromide
• Synonyms: 2-chloro-4-iodobenzyl bromide
• CAS NO: 135049-84-2
• Molecular Weight: 331.378
• Mol File: 135049-84-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-chloro-4-iodobenzyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-4-iodobenzyl bromide(135049-84-2)
• EPA Substance Registry System: 2-chloro-4-iodobenzyl bromide(135049-84-2)

Safety Data

• Hazardous Substances Data: 135049-84-2(Hazardous Substances Data)

Upstream product

• 83846-48-4 3-chloro-4-methyliodobenzene 

Downstream Products

• 279252-27-6 4-chloro-1-(2-chloro-4-iodobenzyl)-2-methylimidazole-5-carbaldehyde 
• 279252-26-5 1-(bromomethyl)-2-chloro-4-(trifluoromethyl)benzene 
• 275384-50-4 2-chloro-4-(1-pentyloxy)benzyl bromide 
• 950482-87-8 2-(2-chloro-4-iodobenzyl)-1H-isoindole-1,3-(2H)-dione 
• 950481-62-6 N-[2-chloro-4-[5-[3,5-bis(trifluoromethyl)phenyl]-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenylmethyl]cyclopropanecarboxamide 
• 950482-91-4 N-[(2-chloro-4-hydroxyiminomethylphenyl)methyl] cyclopropanecarboxamide 
• 950482-90-3 N-[(2-chloro-4-formylphenyl)methyl] cyclopropanecarboxamide 
• 950482-88-9 2-chloro-4-iodobenzylamine 
• 245368-22-3 3-(2-chloro-4-iodobenzyl)-5-(methoxycarbonyl)-2-methylindole 
• 219765-74-9 methyl 3-(2-chloro-4-iodobenzyl)-2-methyl-3H-imidazo[4,5-b]pyridine-5-carboxylate 
• 345635-50-9 2-chloro-4-iodobenzyl methyl sulfide 

Relevant articles and documents

2-(1,2,3-TRIAZOL-2-YL)BENZAMIDE AND 3-(1,2,3-TRIAZOL-2-YL)PICOLINAMIDE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

The present invention relates to 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2- yl)picolinamide derivatives of formula (I) Formula (I) wherein Ar1, Q, and R1 to R5 are as described in the description, to their pre

Sulfonamide compounds and medicinal use thereof

A sulfonamide compound of the formula (I):R 1 --SO 2 NHCO--A--R 2 (I)wherein R 1 is alkyl, alkenyl, alkynyl and the like; A is an optionally substituted heteropolycyclic group except benzimidazolyl, indolyl, 4,7-dihydrobenzimidazolyl and 2,3-dihydrobenzoxazinyl; X is alkylene, oxa, oxa(lower)alkylene and the like; and R 2 is optionally substituted aryl, substituted biphenylyl and the like, a salt thereof and a pharmaceutical composition comprising the same. The sulfonamide compound is effective for the diseases treatable based on their blood sugar level-depressing activity, cGMP-PDE (especially PDE-V)-inhibiting activity, smooth muscle relaxing activity, bronchodilating activity, vasodilating activity, smooth muscle cell suppressing activity, and antiallergic activity.

DIARYL ETHER HETROCYCLES

The invention concerns a diaryl ether heterocycle of the formula I, or a pharmaceutically-acceptable salt thereof, wherein Ar1 is optionally substituted phenyl or naphthyl; X1 is oxy, thio, sulphinyl or sulphonyl; Ar2 is optionally substituted phenylene, or a 6-membered heterocyclene moiety containing up to three nitrogen atoms; Rl is (l-6C)alkyl, (3-6C)alkenyl, (3-6C)alkynyl, cyano-(l-4C)alkyl or (2-4C)alkanoyl, or optionally substituted benzoyl; and R2 and R3 together form a group of the formula ?A2?X2?A3? wherein each of A2 and A3 is (l-4C) alkylene and X2 is oxy, thio, sulphinyl, sulphonyl or imino. The invention also concerns processes for the manufacture of a diaryl ether heterocycle of the formula I, or a pharmaceutically-acceptable salt thereof, and pharmaceutical compositions containing said heterocycle. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.