135077-21-3

Basic information

• Product Name: N^α-tert-butoxycarbonyl-O-benzyl-threonyl-N^ε-benzyloxycarbonyl-lysine benzyl ester
• Synonyms: N^α-tert-butoxycarbonyl-O-benzyl-threonyl-N^ε-benzyloxycarbonyl-lysine benzyl ester
• CAS NO: 135077-21-3
• Molecular Weight: 661.795
• Mol File: 135077-21-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N^α-tert-butoxycarbonyl-O-benzyl-threonyl-N^ε-benzyloxycarbonyl-lysine benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N^α-tert-butoxycarbonyl-O-benzyl-threonyl-N^ε-benzyloxycarbonyl-lysine benzyl ester(135077-21-3)
• EPA Substance Registry System: N^α-tert-butoxycarbonyl-O-benzyl-threonyl-N^ε-benzyloxycarbonyl-lysine benzyl ester(135077-21-3)

Safety Data

• Hazardous Substances Data: 135077-21-3(Hazardous Substances Data)

Upstream product

• 15260-10-3 N-Boc-O-benzyl-L-threonine 
• 6366-70-7 N^ε-carbobenzoxy-L-lysine benzyl ester hydrochloride 
• 77236-13-6 N-α-tert-Butyloxycarbonyl-N-ε-carbobenzoxy-L-lysine benzyl ester 
• 2592-18-9 Boc-Thr-OH 
• 100-44-7 benzyl chloride 
• 2389-45-9 Boc-Lys(Z)-OH 
• 24458-14-8 Lys(Z)-OBzl 

Downstream Products

• 135077-22-4 N^α-tert-butoxycarbonyl-Cγ-tert-butoxyglutamyl-O-benzyl-threonyl-N^ε-benzyloxycarbonyl-lysine benzyl ester 
• 135048-66-7 (S)-2-((2S,3R)-2-Amino-3-benzyloxy-butyrylamino)-6-benzyloxycarbonylamino-hexanoic acid benzyl ester 

Relevant articles and documents

Synthesis of the Tripeptides Tyr-Thr-Lys Phosphorylated with Isopropyl Methyl- and (Deuteromethyl)phosphonochloridates as Reference Standards for the Analysis of Biomedical Samples

A procedure for the phosphorylation of the tripeptide Tyr-Thr-Lys with isopropyl methyl- or (deuteromethyl)phosphonochloridate is developed. The phosphorylated tripeptides are intended for use as reference standards in the analysis of blood samples of people suspected to have been exposed to acetylcholinesterase inhibitors. Conditions of hromatographic separation and purification of the synthesized compounds are determined and optimized, which ensures the preparation of high-purity phosphorylated tripeptides.