1350880-18-0

Basic information

• Product Name: 1-{3-[3-(4-fluorophenyl)-1-(pyrimidin-2-yl)-1H-pyrazol-5-yl]piperidin-1-yl}-2-[4-(trifluoromethyl)phenyl]ethanone
• Synonyms: 1-{3-[3-(4-fluorophenyl)-1-(pyrimidin-2-yl)-1H-pyrazol-5-yl]piperidin-1-yl}-2-[4-(trifluoromethyl)phenyl]ethanone
• CAS NO: 1350880-18-0
• Molecular Weight: 509.506
• Mol File: 1350880-18-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-{3-[3-(4-fluorophenyl)-1-(pyrimidin-2-yl)-1H-pyrazol-5-yl]piperidin-1-yl}-2-[4-(trifluoromethyl)phenyl]ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{3-[3-(4-fluorophenyl)-1-(pyrimidin-2-yl)-1H-pyrazol-5-yl]piperidin-1-yl}-2-[4-(trifluoromethyl)phenyl]ethanone(1350880-18-0)
• EPA Substance Registry System: 1-{3-[3-(4-fluorophenyl)-1-(pyrimidin-2-yl)-1H-pyrazol-5-yl]piperidin-1-yl}-2-[4-(trifluoromethyl)phenyl]ethanone(1350880-18-0)

Safety Data

• Hazardous Substances Data: 1350880-18-0(Hazardous Substances Data)

Upstream product

• 1350881-16-1 tert-butyl 3-[3-(4-fluorophenyl)prop-2-ynoyl]piperidine-1-carboxylate 
• 1350881-18-3 tert-butyl 3-[3-(4-fluorophenyl)-1-(pyrimidin-2-yl)-1H-pyrazol-5-yl]piperidine-1-carboxylate 
• 1350881-17-2 tert-butyl 5-[3-(4-fluorophenyl)-1H-pyrazol-5-yl]piperidine-1-carboxylate 
• 189442-78-2 (±)-tert-butyl 3-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 71381-75-4 N-(tert-butyloxycarbonyl)nipecotic acid 
• 1350881-12-7 2-[3-(4-fluorophenyl)-5-(piperidin-3-yl)-1H-pyrazoI-1-yl]pyrimidine 
• 32857-62-8 4-Trifluoromethylphenylacetic acid 

Relevant articles and documents

NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS

Compounds of structural formula I are inhibitors of prolylcarboxypeptidase (PrCP). The compounds of the present invention are useful for the prevention and treatment of conditions related to the enzymatic activity of PrCP such as abnormal metabolism, including obesity; diabetes; metabolic syndrome; obesity related disorders; and diabetes related disorders.