1350896-29-5Relevant academic research and scientific papers
Esterase-sensitive sulfur dioxide prodrugs inspired by modified Julia olefination
Wang, Wenyi,Wang, Binghe
, p. 10124 - 10127 (2017/09/23)
Sulfur dioxide (SO2) is an endogenously produced gaseous molecule, and is emerging as a potential gasotransmitter. Herein, we describe the first series of esterase-sensitive prodrugs inspired by modified Julia olefination as SO2 donors.
A metal-free, aqueous and general route to 1,5-disubstituted-1,2,3- triazoles: "Reversed regioisomeric" 1,3-dipolar cycloaddition of azides and vinyl sulfones
Dey, Santu,Datta, Dhrubajyoti,Pathak, Tanmaya
supporting information; experimental part, p. 2521 - 2524 (2011/12/01)
A metal-free, vinyl sulfone-based synthesis of 1,5-disubstituted-1,2,3- triazoles is reported for the first time. These triazoles are easily formed in a regioselective fashion by heating under reflux a mixture of a substituted vinyl sulfone and an organic
Thermal reactions of β-hydroxysulfides bearing benzothiazole: Sulfenic acid trapping via a spiro intermediate
Yamada, Nobuhiko,Koyasu, Takanori,Sonami, Mayumi,Aoi, Michiko,Tashiro, Shintaro,Sheikh, Md. Chanmiya,Ishida, Yusuke,Kawashima, Wataru,Yoshimura, Toshiaki,Morita, Hiroyuki
body text, p. 1142 - 1153 (2010/08/21)
Benzothiazolyl 2-hydroxyethyl sulfoxide (1a) was found to afford bis[2-(2-oxobenzotiazolyl)-ethyl] disulfide (2a) in the presence of DBU at rt. 2a was formed by the condensation of corresponding sulfenic acid intermediate. Thermolyses of 1a in the presence of ethyl propiolate at 60-140C were carried out to succeed to trap sulfenic acid 6a as an intermediate. Trapping of 2-benzothiazolyloxyenthanesulfenic acid (6a) revealed that the thermal reaction proceeded via a five-membered spiro intermediate 5a. Copyright Taylor & Francis Group.
