1350897-58-3Relevant academic research and scientific papers
Synthesis of furo[2,3-b]pyridine
Chang, Meng-Yang,Tai, Hang-Yi
, p. 2373 - 2380 (2011/11/06)
Two synthetic routes toward furo[2,3-b]pyridine (1) starting with the known β,γ-unsaturated ester (3) are described.
Synthesis of rodocaine
Chang, Meng-Yang,Tai, Hang-Yi,Chen, Yeh-Long
, p. 7673 - 7680 (2011/10/12)
A new method for synthesis of rodocaine (1) is presented. Two key steps were carried out by the N-bromosuccinimide (NBS)-mediated intermolecular addition of known enamine 5 with allyltrimethyl silane in presence of boron trifluoride etherate (BF3/OEt2) and the intramolecular ring-closing metathesis of triene 3. The Diels-Alder cycloaddition of triene 3 with different ethyl propiolates was also studied.
