267666-10-4

Basic information

• Product Name: N-benzenesulfonyl-3-piperidone
• Synonyms: N-benzenesulfonyl-3-piperidone
• CAS NO: 267666-10-4
• Molecular Weight: 239.295
• Mol File: 267666-10-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-benzenesulfonyl-3-piperidone(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzenesulfonyl-3-piperidone(267666-10-4)
• EPA Substance Registry System: N-benzenesulfonyl-3-piperidone(267666-10-4)

Safety Data

• Hazardous Substances Data: 267666-10-4(Hazardous Substances Data)

Upstream product

• 64051-79-2 piperidin-3-ol hydrochloride 
• 98-09-9 benzenesulfonyl chloride 
• 6859-99-0 3-hydroxypiperazine 
• 1021372-74-6 1-(phenylsulfonyl)piperidin-3-ol 

Downstream Products

• 1027657-45-9 1-benzenesulfonyl-3,3-dimethoxy-piperidine 
• 1268245-93-7 (1-benzenesulfonyl-1,4,5,6-tetrahydro-pyridin-3-yl)-acetic acid ethyl ester 
• 272-01-5 furo<2,3-b>pyridine 
• 1350897-58-3 2-(1-benzenesulfonyl-1,4,5,6-tetrahydropyridin-3-yl)ethanol 
• 1350897-60-7 7-benzenesulfonyl-4,5,6,7-tetrahydrofuro[2,3-b]pyridine 
• 1429122-71-3 C₁₄H₁₇NO₃S 
• 1429122-74-6 1-(phenylsulfonyl)-3-(prop-2-yn-1-yl)piperidin-3-ol 
• 1335288-20-4 C₁₅H₁₉NO₄S 
• 267666-39-7 2,9-bis-benzenesulfonyl-6,7-dimethoxy-2,3,4,9-tetrahydro-1H-β-carboline 
• 267666-56-8 9-benzenesulfonyl-6,7-dimethoxy-9H-β-carboline 
• 196883-02-0 2,9-bis-benzenesulfonyl-7-methoxy-2,3,4,9-tetrahydro-1H-β-carbolin-6-ol 
• 196882-98-1 1-Benzenesulfonyl-5-methoxy-1,2,3,6-tetrahydro-pyridine 

Relevant articles and documents

Synthesis of 1,2,4-trisubstituted-1,2,5,6-tetrahydropyridines

A novel method for the synthesis of 1,2,4-trisubstituted- or 1,2,3,4-tetrasubstituted-1,2,5,6-tetrahydropyridine is presented. The process was carried out by the bromomethoxylation of 4-substituted-1,2,5,6- tetrahydropyridines 1 with N-bromosuccinimide (NBS) in methanol, dehydrobromination with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), and boron trifluoride etherate (BF3-OEt2)-catalyzed cross coupling of the corresponding enamine with trimethylsilyl-based nucleophiles. Homokainoid analogs were also synthesized via the protocol.

Lewis Acid-Directed Cyclocondensation of Piperidone Enol Ethers with 2-Methoxy-4-(N-phenylsulfonyl)-1,4-benzoquinoneimine: A New Regioselective Synthesis of Oxygenated Carbolines

Lewis acid-directed cyclocondensations of piperidone enol ethers with 2-methoxy-4-(N-phenylsulfonyl)-1,4-henzoquinoneimine are reported. Benzofurans are obtained with BF3·OEt2 as a promoter, whereas use of excess amounts of TiCl4:Ti(OiPr)4 leads to tetrahydrocarbolines. The latter reactions provide expedient routes to oxygen-substituted tetrahydrocarbolines and carbolines. As applications of this new methodology, the preparations of 1-[3-(dimethylamino)propyl]amino-7-methoxy- and 1-[3-(dimethylamino)propyl]amino-7,8-dimethoxy-5H-pyrido[4,3-b]indoles are described.