135131-03-2Relevant academic research and scientific papers
Synthesis and aldose reductase inhibitory activity of triazine derivatives possessing acetic acid group
Mavel,Coudert,Albuisson,Duroux,Bastide,Couquelet,Tronche,Rubat
, p. 1411 - 1414 (1992)
N-Acetic acid derivatives of 6-aryl-pyrazolo-triazin-4-ones were synthesized for evaluation as new aldose reductase inhibitors. The intrinsic activity of each compound was assessed by measuring the inhibition of enzymatic activity in an isolated pig lens
Synthesis of New 2-Aryl-3,3a-dihydro-4-oxo-5H-pyrazolotriazines and some of Their Derivatives
Coudert, P.,Mavel, S.,Couquelet, J.,Tronche, P.,Rubat, C.,Bastide, J.
, p. 769 - 772 (2007/10/02)
The preparation of new dihydropyrazolotriazinones involved the formation of carboxylic acid hydrazides via the appropriate ethyl aroylacrylates, followed by condensation with an orthoester.The synthesis of some derivatives substituted on the
