Synthesis and aldose reductase inhibitory activity of triazine derivatives possessing acetic acid group

DOI: 10.1248/cpb.40.1411

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1411 - 1414 (1992)

Update date:2022-08-04

Topics:

Authors:

Mavel Mavel

Coudert Coudert

Albuisson

Duroux Duroux

Bastide Bastide

Couquelet

Tronche Tronche

Rubat Rubat

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Article abstract of DOI:10.1248/cpb.40.1411

N-Acetic acid derivatives of 6-aryl-pyrazolo-triazin-4-ones were synthesized for evaluation as new aldose reductase inhibitors. The intrinsic activity of each compound was assessed by measuring the inhibition of enzymatic activity in an isolated pig lens

Full text of DOI:10.1248/cpb.40.1411

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Product name:2-Phenyl-3,3a-dihydro-4-oxopyrazolo<1,5-d><1,2,4>triazin-5-ylacetic Acid Ethyl Ester

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