135182-06-8

Upstream product

• 135181-98-5 N-benzyl-2-(4-methoxyphenyl)-N-methylacetamide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 6798-05-6 2-methyl-1,4-dihydro-2H-isoquinolin-3-one 
• 4693-91-8 4-methoxyphenyl-acetic chloride 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

A facile synthesis of 4-aryl-1,2,3,4-tetrahydroisoquinolines

A facile and versatile palladium catalyzed α-arylation between dihydroisoquinolinones and various aryl halides is described. Combined with borane reduction, it provides a convenient way to prepare 4-aryl-1,2,3,4- tetrahydroisoquinolines.

Synthesis of 4-aryl-1,4-dihydro-3(2H)-isoquinolinones by oxidative cyclization of N-benzylaraylacetamides

4-Aryl-1,4-dihydro-3(2H)-isoquinolinones are obtained by oxidative cyclization of N-benzyl-N-alkylarylacetamides with lead tetraacetate in acetic acid/trifluoroacetic acid.