1351982-01-8Relevant academic research and scientific papers
PREPARATION OF 2-METHYL-4-AMINO-5(SUBSTITUTED-1H-1,2,3-TRIAZOLYL)METHYLPYRIMIDINE DERIVATIVES AND MICROBICIDAL ACTIVITY THEREOF
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Paragraph 0031-0037, (2014/07/22)
Disclosed is a derivative of 2-methyl-4-amino-5-(substituted-1H-1,2,3-triazol)methylpyrimidine of general formula I and microbicidal activity thereof. In the formula, R1 represents hydrogen, I; X represents O or NH; Y represents phenyl of substituted phen
Structure-based rational design of novel hit compounds for pyruvate dehydrogenase multienzyme complex E1 components from Escherichia coli
Ren, Yanliang,He, Junbo,Feng, Lingling,Liao, Xun,Jin, Jing,Li, Yongjian,Cao, Yi,Wan, Jian,He, Hongwu
, p. 7501 - 7506 (2012/01/03)
Pyruvate dehydrogenase multienzyme complex (PDHc) E1 component plays a pivotal role in cellular metabolism to convert the product of glycolysis (pyruvate) to acetyl-CoA, and has been reported as a potential target for anti-microbial and herbicide. In pres
