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3,4-Dihydro Agomelatine is a chemical compound derived from agomelatine, an antidepressant and anxiolytic medication. It acts as a potent and selective agonist of the melatonin receptors MT1 and MT2, and a weak antagonist of the 5-HT2C receptors. 3,4-Dihydro Agomelatine has demonstrated improved pharmacokinetic properties and a longer half-life than agomelatine, which may enhance its effectiveness and duration of action. Preclinical studies have shown promising results for the treatment of depression and anxiety disorders, although further research is required to fully understand its therapeutic potential and safety profile in clinical settings.

1352139-51-5

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1352139-51-5 Usage

Uses

Used in Pharmaceutical Industry:
3,4-Dihydro Agomelatine is used as a potential antidepressant and anxiolytic agent for its ability to selectively activate melatonin receptors MT1 and MT2, and weakly antagonize the 5-HT2C receptors. This dual mechanism of action may contribute to its effectiveness in treating depression and anxiety disorders.
Used in Preclinical Research:
3,4-Dihydro Agomelatine is used as a subject of preclinical studies to evaluate its therapeutic potential, effectiveness, and safety profile in treating depression and anxiety disorders. These studies aim to provide insights into its pharmacological properties and pave the way for future clinical trials and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1352139-51-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,2,1,3 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1352139-51:
(9*1)+(8*3)+(7*5)+(6*2)+(5*1)+(4*3)+(3*9)+(2*5)+(1*1)=135
135 % 10 = 5
So 1352139-51-5 is a valid CAS Registry Number.

1352139-51-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[2-(7-methoxy-3,4-dihydro-naphthalen-1-yl)ethyl]acetamide

1.2 Other means of identification

Product number -
Other names .N-[2-(7-methoxy-3,4-dihydro-1-naphthyl)ethyl]acetamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1352139-51-5 SDS

1352139-51-5Relevant articles and documents

PROCESSES FOR THE PREPARATION OF N-[2-(7-METHOXY-1-NAPHTHYL)ETHYL]ACETAMIDE

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, (2012/07/27)

The present invention relates to processes for the synthesis of N-[2-(7-methoxy-l - naphthethyl] acetamide, amorphous form of N-[2-(7-methoxy-l -naphthethyl] acetamide and pharmaceutical compositions thereof.

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